ENSG00000197063


Homo sapiens

Features
Gene ID: ENSG00000197063
  
Biological name :MAFG
  
Synonyms : MAF bZIP transcription factor G / MAFG / O15525
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q25.3
Gene start: 81918270
Gene end: 81927714
  
Corresponding Affymetrix probe sets: 204970_s_at (Human Genome U133 Plus 2.0 Array)   224466_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000459634
Ensembl peptide - ENSP00000350369
Ensembl peptide - ENSP00000376173
NCBI entrez gene - 4097     See in Manteia.
OMIM - 602020
RefSeq - XM_011523578
RefSeq - NM_002359
RefSeq - NM_032711
RefSeq Peptide - NP_002350
RefSeq Peptide - NP_116100
swissprot - A0A024R8X1
swissprot - I3L2F8
swissprot - O15525
Ensembl - ENSG00000197063
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mafgaENSDARG00000018109Danio rerio
 mafgbENSDARG00000100097Danio rerio
 MAFGENSGALG00000031475Gallus gallus
 MafgENSMUSG00000051510Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAFK / O60675 / MAF bZIP transcription factor KENSG0000019851772
MAFF / Q9ULX9 / MAF bZIP transcription factor FENSG0000018502260
MAF / O75444 / MAF bZIP transcription factorENSG0000017857341
MAFB / Q9Y5Q3 / MAF bZIP transcription factor BENSG0000020410340
MAFA / Q8NHW3 / MAF bZIP transcription factor AENSG0000018275938
NRL / P54845 / neural retina leucine zipperENSG0000012953534


Protein motifs (from Interpro)
Interpro ID Name
 IPR004826  Basic leucine zipper domain, Maf-type
 IPR004827  Basic-leucine zipper domain
 IPR008917  Transcription factor, Skn-1-like, DNA-binding domain superfamily
 IPR024874  Transcription factor Maf family
 IPR028551  Transcription factor MafG


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0030534 adult behavior IEA
 biological_processGO:0030641 regulation of cellular pH IEA
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0045604 regulation of epidermal cell differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000123405 NFE2 / Q16621 / nuclear factor, erythroid 2  / reaction / complex






 

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