ENSG00000197381


Homo sapiens

Features
Gene ID: ENSG00000197381
  
Biological name :ADARB1
  
Synonyms : ADARB1 / adenosine deaminase, RNA specific B1 / P78563
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: 1
Band: q22.3
Gene start: 45073853
Gene end: 45226560
  
Corresponding Affymetrix probe sets: 203865_s_at (Human Genome U133 Plus 2.0 Array)   207999_s_at (Human Genome U133 Plus 2.0 Array)   209979_at (Human Genome U133 Plus 2.0 Array)   234539_at (Human Genome U133 Plus 2.0 Array)   234799_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000478160
Ensembl peptide - ENSP00000436367
Ensembl peptide - ENSP00000486475
Ensembl peptide - ENSP00000015877
Ensembl peptide - ENSP00000353920
Ensembl peptide - ENSP00000374513
Ensembl peptide - ENSP00000387480
Ensembl peptide - ENSP00000414600
Ensembl peptide - ENSP00000435381
NCBI entrez gene - 104     See in Manteia.
OMIM - 601218
RefSeq - XM_017028256
RefSeq - NM_001112
RefSeq - NM_001160230
RefSeq - NM_015833
RefSeq - NM_015834
RefSeq - XM_017028249
RefSeq - XM_017028250
RefSeq - XM_017028251
RefSeq - XM_017028252
RefSeq - XM_017028253
RefSeq - XM_017028254
RefSeq - XM_017028255
RefSeq - XM_006723954
RefSeq - XM_011529425
RefSeq - XM_011529432
RefSeq - XM_017028242
RefSeq - XM_017028243
RefSeq - XM_017028244
RefSeq - XM_017028245
RefSeq - XM_017028246
RefSeq - XM_017028247
RefSeq - XM_017028248
RefSeq Peptide - NP_001103
RefSeq Peptide - NP_001153702
RefSeq Peptide - NP_056648
RefSeq Peptide - NP_056649
swissprot - P78563
swissprot - Q8TCX7
swissprot - A0A0A0MSG8
Ensembl - ENSG00000197381
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adarb1aENSDARG00000041609Danio rerio
 adarb1bENSDARG00000003544Danio rerio
 ADARB1ENSGALG00000007527Gallus gallus
 Adarb1ENSMUSG00000020262Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ADARB2 / Q9NS39 / adenosine deaminase, RNA specific B2 (inactive)ENSG0000018573650
ADAR / P55265 / adenosine deaminase, RNA specificENSG0000016071030
ADAD2 / Q8NCV1 / adenosine deaminase domain containing 2ENSG0000014095521
ADAD1 / Q96M93 / adenosine deaminase domain containing 1ENSG0000016411320
ADAT1 / Q9BUB4 / adenosine deaminase, tRNA specific 1ENSG0000006545715


Protein motifs (from Interpro)
Interpro ID Name
 IPR002466  Adenosine deaminase/editase
 IPR008996  Cytokine IL1/FGF
 IPR014720  Double-stranded RNA-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006382 adenosine to inosine editing TAS
 biological_processGO:0006396 RNA processing IEA
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0007274 neuromuscular synaptic transmission IEA
 biological_processGO:0008285 negative regulation of cell proliferation IDA
 biological_processGO:0021610 facial nerve morphogenesis IEA
 biological_processGO:0021618 hypoglossal nerve morphogenesis IEA
 biological_processGO:0021965 spinal cord ventral commissure morphogenesis IEA
 biological_processGO:0030336 negative regulation of cell migration IDA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation IDA
 biological_processGO:0045070 positive regulation of viral genome replication IMP
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050884 neuromuscular process controlling posture IEA
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0051726 regulation of cell cycle IDA
 biological_processGO:0060384 innervation IEA
 biological_processGO:0060415 muscle tissue morphogenesis IEA
 biological_processGO:0061744 motor behavior IEA
 biological_processGO:0097049 motor neuron apoptotic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003726 double-stranded RNA adenosine deaminase activity TAS
 molecular_functionGO:0003729 mRNA binding TAS
 molecular_functionGO:0004000 adenosine deaminase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
C6 deamination of adenosine
Formation of editosomes by ADAR proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000197381 ADARB1 / P78563 / adenosine deaminase, RNA specific B1  / complex / reaction






 

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