ENSG00000197901


Homo sapiens

Features
Gene ID: ENSG00000197901
  
Biological name :SLC22A6
  
Synonyms : Q4U2R8 / SLC22A6 / solute carrier family 22 member 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q12.3
Gene start: 62936385
Gene end: 62984983
  
Corresponding Affymetrix probe sets: 210343_s_at (Human Genome U133 Plus 2.0 Array)   216599_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000367102
Ensembl peptide - ENSP00000404441
Ensembl peptide - ENSP00000445946
Ensembl peptide - ENSP00000353597
Ensembl peptide - ENSP00000396401
NCBI entrez gene - 9356     See in Manteia.
OMIM - 607582
RefSeq - XM_017018562
RefSeq - NM_004790
RefSeq - NM_153276
RefSeq - NM_153277
RefSeq - NM_153278
RefSeq Peptide - NP_004781
RefSeq Peptide - NP_695008
RefSeq Peptide - NP_695009
RefSeq Peptide - NP_695010
swissprot - Q4U2R8
swissprot - F5H0T7
Ensembl - ENSG00000197901
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 oatxENSDARG00000019713Danio rerio
 slc22a6lENSDARG00000055523Danio rerio
 Q8VC69ENSMUSG00000024650Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8TCC7 / SLC22A8 / solute carrier family 22 member 8ENSG0000014945249
Q96S37 / SLC22A12 / solute carrier family 22 member 12ENSG0000019789143
Q9NSA0 / SLC22A11 / solute carrier family 22 member 11ENSG0000016806540
Q8N4F4 / SLC22A24 / solute carrier family 22 member 24ENSG0000019765838
Q63ZE4 / SLC22A10 / solute carrier family 22 member 10ENSG0000018499937
Q9Y694 / SLC22A7 / solute carrier family 22 member 7ENSG0000013720437
Q8IVM8 / SLC22A9 / solute carrier family 22 member 9ENSG0000014974236
Q6T423 / SLC22A25 / solute carrier family 22 member 25ENSG0000019660036
Q9Y226 / SLC22A13 / solute carrier family 22 member 13ENSG0000017294033
O15244 / SLC22A2 / solute carrier family 22 member 2ENSG0000011249931
O15245 / SLC22A1 / solute carrier family 22 member 1ENSG0000017500330
O75751 / SLC22A3 / solute carrier family 22 member 3ENSG0000014647730
O76082 / SLC22A5 / solute carrier family 22 member 5ENSG0000019737528
Q8IZD6 / SLC22A15 / solute carrier family 22 member 15ENSG0000016339327
Q9Y267 / SLC22A14 / solute carrier family 22 member 14ENSG0000014467127
Q86VW1 / SLC22A16 / solute carrier family 22 member 16ENSG0000000480926
Q9H015 / SLC22A4 / solute carrier family 22 member 4ENSG0000019720826


Protein motifs (from Interpro)
Interpro ID Name
 IPR004749  Organic cation transport protein/SVOP
 IPR005828  Major facilitator, sugar transporter-like
 IPR020846  Major facilitator superfamily domain
 IPR036259  MFS transporter superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006820 anion transport IEA
 biological_processGO:0015698 inorganic anion transport IEA
 biological_processGO:0015711 organic anion transport IMP
 biological_processGO:0015742 alpha-ketoglutarate transport IDA
 biological_processGO:0015747 urate transport IBA
 biological_processGO:0031427 response to methotrexate IEA
 biological_processGO:0043252 sodium-independent organic anion transport IBA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0097254 renal tubular secretion NAS
 biological_processGO:0098656 anion transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0005901 caveola IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005452 inorganic anion exchanger activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008514 organic anion transmembrane transporter activity IMP
 molecular_functionGO:0015143 urate transmembrane transporter activity IBA
 molecular_functionGO:0015301 anion:anion antiporter activity TAS
 molecular_functionGO:0015347 sodium-independent organic anion transmembrane transporter activity IBA
 molecular_functionGO:0022857 transmembrane transporter activity IEA
 molecular_functionGO:0031404 chloride ion binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA


Pathways (from Reactome)
Pathway description
Organic anion transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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