ENSG00000204060


Homo sapiens

Features
Gene ID: ENSG00000204060
  
Biological name :FOXO6
  
Synonyms : A8MYZ6 / forkhead box O6 / FOXO6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p34.2
Gene start: 41361922
Gene end: 41383590
  
Corresponding Affymetrix probe sets: 239657_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000493184
NCBI entrez gene - 100132074     See in Manteia.
OMIM - 611457
RefSeq - NM_001291281
RefSeq Peptide - NP_001278210
swissprot - A8MYZ6
Ensembl - ENSG00000204060
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 foxo6aENSDARG00000100486Danio rerio
 foxo6bENSDARG00000024619Danio rerio
 FOXO6ENSGALG00000026153Gallus gallus
 Foxo6ENSMUSG00000052135Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FOXO3 / O43524 / forkhead box O3ENSG0000011868945
FOXO1 / Q12778 / forkhead box O1ENSG0000015090739
FOXO4 / P98177 / forkhead box O4ENSG0000018448136
FOXM1 / Q08050 / forkhead box M1ENSG0000011120620


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR030456  Fork head domain conserved site 2
 IPR032067  FOXO protein, transactivation domain
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0060999 positive regulation of dendritic spine development IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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