ENSG00000211460


Homo sapiens

Features
Gene ID: ENSG00000211460
  
Biological name :TSN
  
Synonyms : Q15631 / translin / TSN
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q14.3
Gene start: 121737103
Gene end: 121767853
  
Corresponding Affymetrix probe sets: 201504_s_at (Human Genome U133 Plus 2.0 Array)   201513_at (Human Genome U133 Plus 2.0 Array)   201515_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000437728
Ensembl peptide - ENSP00000487702
Ensembl peptide - ENSP00000488237
Ensembl peptide - ENSP00000487833
Ensembl peptide - ENSP00000487808
Ensembl peptide - ENSP00000374332
Ensembl peptide - ENSP00000387263
Ensembl peptide - ENSP00000399735
NCBI entrez gene - 7247     See in Manteia.
OMIM - 600575
RefSeq - NM_004622
RefSeq - NM_001261401
RefSeq Peptide - NP_001248330
RefSeq Peptide - NP_004613
swissprot - E9PGT1
swissprot - Q15631
swissprot - A0A0J9YX41
swissprot - A0A0J9YVW2
swissprot - H7C1D4
Ensembl - ENSG00000211460
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tsnENSDARG00000041830Danio rerio
 TSNENSGALG00000011652Gallus gallus
 TsnENSMUSG00000026374Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002848  Translin family
 IPR016068  Translin, N-terminal
 IPR033956  Translin
 IPR036081  Translin superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006310 DNA recombination TAS
 biological_processGO:0016070 RNA metabolic process IEA
 biological_processGO:0030422 production of siRNA involved in RNA interference TAS
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0003677 DNA binding TAS
 molecular_functionGO:0003697 single-stranded DNA binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004519 endonuclease activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
Small interfering RNA (siRNA) biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000211460 TSN / Q15631 / translin  / complex
 ENSG00000116918 TSNAX / Q99598 / translin associated factor X  / complex
 ENSG00000123908 AGO2 / Q9UKV8 / argonaute 2, RISC catalytic component  / reaction






 

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