ENSG00000215397


Homo sapiens

Features
Gene ID: ENSG00000215397
  
Biological name :SCRT2
  
Synonyms : Q9NQ03 / scratch family transcriptional repressor 2 / SCRT2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: p13
Gene start: 661596
Gene end: 676179
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000246104
NCBI entrez gene - 85508     See in Manteia.
RefSeq - NM_033129
RefSeq Peptide - NP_149120
swissprot - Q9NQ03
Ensembl - ENSG00000215397
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scrt2ENSDARG00000056175Danio rerio
 SCRT2ENSGALG00000028912Gallus gallus
 Scrt2ENSMUSG00000060257Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SCRT1 / Q9BWW7 / scratch family transcriptional repressor 1ENSG0000026167863
SNAI2 / O43623 / snail family transcriptional repressor 2ENSG0000001954934
SNAI3 / Q3KNW1 / snail family transcriptional repressor 3ENSG0000018566931
SNAI1 / O95863 / snail family transcriptional repressor 1ENSG0000012421630


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR029794  Transcriptional repressor SCRATCH 1/2
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors ISS
 biological_processGO:2001222 regulation of neuron migration IEA
 cellular_componentGO:0000790 nuclear chromatin ISS
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IC
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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