ENSG00000261678


Homo sapiens

Features
Gene ID: ENSG00000261678
  
Biological name :SCRT1
  
Synonyms : Q9BWW7 / scratch family transcriptional repressor 1 / SCRT1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q24.3
Gene start: 144330565
Gene end: 144336281
  
Corresponding Affymetrix probe sets: 221026_s_at (Human Genome U133 Plus 2.0 Array)   228761_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000455711
NCBI entrez gene - 83482     See in Manteia.
OMIM - 605858
RefSeq - NM_031309
RefSeq Peptide - NP_112599
swissprot - Q9BWW7
Ensembl - ENSG00000261678
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scrt1aENSDARG00000100821Danio rerio
 scrt1bENSDARG00000040214Danio rerio
 Scrt1ENSMUSG00000048385Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SCRT2 / Q9NQ03 / scratch family transcriptional repressor 2ENSG0000021539756
SNAI2 / O43623 / snail family transcriptional repressor 2ENSG0000001954929
SNAI3 / Q3KNW1 / snail family transcriptional repressor 3ENSG0000018566928
SNAI1 / O95863 / snail family transcriptional repressor 1ENSG0000012421625


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR029794  Transcriptional repressor SCRATCH 1/2
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated TAS
 biological_processGO:2001222 regulation of neuron migration IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0016604 nuclear body IDA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity NAS
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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