ENSMUSG00000048385


Mus musculus

Features
Gene ID: ENSMUSG00000048385
  
Biological name :Scrt1
  
Synonyms : Q99M85 / Scrt1 / Transcriptional repressor scratch 1
  
Possible biological names infered from orthology : Q9BWW7 / scratch family transcriptional repressor 1
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: D3
Gene start: 76516203
Gene end: 76522499
  
Corresponding Affymetrix probe sets: 10429944 (MoGene1.0st)   1421368_at (Mouse Genome 430 2.0 Array)   1436084_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000094093
Ensembl peptide - ENSMUSP00000131152
NCBI entrez gene - 170729     See in Manteia.
MGI - MGI:2176606
RefSeq - NM_130893
RefSeq Peptide - NP_570963
swissprot - Q99M85
Ensembl - ENSMUSG00000048385
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 scrt1aENSDARG00000100821Danio rerio
 scrt1bENSDARG00000040214Danio rerio
 SCRT1ENSG00000261678Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Scrt2 / Q8BTH6 / Transcriptional repressor scratch 2 / Q9NQ03* / scratch family transcriptional repressor 2*ENSMUSG0000006025754
Snai2 / P97469 / snail family zinc finger 2 / O43623* / snail family transcriptional repressor 2*ENSMUSG0000002267629
Snai3 / Q9QY31 / Zinc finger protein SNAI3 / Q3KNW1* / snail family transcriptional repressor 3*ENSMUSG0000000658726
Snai1 / Q02085 / snail family zinc finger 1 / O95863* / snail family transcriptional repressor 1*ENSMUSG0000004282125


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR029794  Transcriptional repressor SCRATCH 1/2
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:2001222 regulation of neuron migration IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0016604 nuclear body ISO
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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