ENSG00000242550


Homo sapiens

Features
Gene ID: ENSG00000242550
  
Biological name :SERPINB10
  
Synonyms : P48595 / SERPINB10 / serpin family B member 10
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q21.33
Gene start: 63897174
Gene end: 63936111
  
Corresponding Affymetrix probe sets: 214539_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000238508
Ensembl peptide - ENSP00000381082
Ensembl peptide - ENSP00000392381
Ensembl peptide - ENSP00000479385
NCBI entrez gene - 5273     See in Manteia.
OMIM - 602058
RefSeq - XM_017025794
RefSeq - NM_005024
RefSeq - XM_011526027
RefSeq - XM_017025793
RefSeq Peptide - NP_005015
swissprot - P48595
swissprot - H7C004
swissprot - H7BYS2
Ensembl - ENSG00000242550
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000019554Gallus gallus
 O73790ENSGALG00000019553Gallus gallus
 Serpinb10ENSMUSG00000092572Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P05120 / SERPINB2 / serpin family B member 2ENSG0000019763248
P35237 / SERPINB6 / serpin family B member 6ENSG0000012457045
P30740 / SERPINB1 / serpin family B member 1ENSG0000002135545
P50452 / SERPINB8 / serpin family B member 8ENSG0000016640144
P50453 / SERPINB9 / serpin family B member 9ENSG0000017054244
P48594 / SERPINB4 / serpin family B member 4ENSG0000020607344
P29508 / SERPINB3 / serpin family B member 3ENSG0000005714944
Q9UIV8 / SERPINB13 / serpin family B member 13ENSG0000019764144
P36952 / SERPINB5 / serpin family B member 5ENSG0000020607535


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR015556  Plasminogen activator inhibitor-2
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain
 IPR036186  Serpin superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0030667 secretory granule membrane TAS
 cellular_componentGO:0101003 ficolin-1-rich granule membrane TAS
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity TAS
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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