ENSG00000197641


Homo sapiens

Features
Gene ID: ENSG00000197641
  
Biological name :SERPINB13
  
Synonyms : Q9UIV8 / SERPINB13 / serpin family B member 13
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q21.33
Gene start: 63586989
Gene end: 63604639
  
Corresponding Affymetrix probe sets: 211361_s_at (Human Genome U133 Plus 2.0 Array)   211362_s_at (Human Genome U133 Plus 2.0 Array)   215817_at (Human Genome U133 Plus 2.0 Array)   216257_at (Human Genome U133 Plus 2.0 Array)   216258_s_at (Human Genome U133 Plus 2.0 Array)   217272_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000394592
Ensembl peptide - ENSP00000341584
Ensembl peptide - ENSP00000388300
Ensembl peptide - ENSP00000391156
Ensembl peptide - ENSP00000269489
NCBI entrez gene - 5275     See in Manteia.
OMIM - 604445
RefSeq - XM_011526029
RefSeq - NM_001307923
RefSeq - NM_012397
RefSeq - XM_005266707
RefSeq Peptide - NP_036529
RefSeq Peptide - NP_001294852
swissprot - H7BZS9
swissprot - Q9UIV8
swissprot - C9JL93
swissprot - F8WE70
swissprot - A0A0A0MQW3
Ensembl - ENSG00000197641
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8CDC0ENSMUSG00000048775Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P48594 / SERPINB4 / serpin family B member 4ENSG0000020607357
P29508 / SERPINB3 / serpin family B member 3ENSG0000005714956
P30740 / SERPINB1 / serpin family B member 1ENSG0000002135545
P48595 / SERPINB10 / serpin family B member 10ENSG0000024255044
P50453 / SERPINB9 / serpin family B member 9ENSG0000017054242
P35237 / SERPINB6 / serpin family B member 6ENSG0000012457041
P05120 / SERPINB2 / serpin family B member 2ENSG0000019763239
P50452 / SERPINB8 / serpin family B member 8ENSG0000016640138
P36952 / SERPINB5 / serpin family B member 5ENSG0000020607532


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain
 IPR036186  Serpin superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009411 response to UV TAS
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IDA
 biological_processGO:0030162 regulation of proteolysis NAS
 biological_processGO:0045616 regulation of keratinocyte differentiation TAS
 biological_processGO:1902173 negative regulation of keratinocyte apoptotic process IMP
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016607 nuclear speck IDA
 cellular_componentGO:0043202 lysosomal lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0002020 protease binding IPI
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity NAS
 molecular_functionGO:0004869 cysteine-type endopeptidase inhibitor activity IMP
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000143387 CTSK / P43235 / cathepsin K  / complex / reaction
 ENSG00000135047 CTSL / P07711 / cathepsin L  / reaction / complex
 ENSG00000136943 CTSV / O60911 / cathepsin V  / reaction / complex






 

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