ENSG00000170542


Homo sapiens

Features
Gene ID: ENSG00000170542
  
Biological name :SERPINB9
  
Synonyms : P50453 / SERPINB9 / serpin family B member 9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p25.2
Gene start: 2887266
Gene end: 2903280
  
Corresponding Affymetrix probe sets: 209722_s_at (Human Genome U133 Plus 2.0 Array)   209723_at (Human Genome U133 Plus 2.0 Array)   242814_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000370074
NCBI entrez gene - 5272     See in Manteia.
OMIM - 601799
RefSeq - XM_017010943
RefSeq - NM_004155
RefSeq - XM_005249184
RefSeq - XM_011514678
RefSeq - XM_017010942
RefSeq Peptide - NP_004146
swissprot - P50453
swissprot - A0A024QZT4
Ensembl - ENSG00000170542
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 serpinb14ENSDARG00000091801Danio rerio
 serpinb1l1ENSDARG00000095830Danio rerio
 serpinb1l3ENSDARG00000014556Danio rerio
 serpinb1l4ENSDARG00000096888Danio rerio
 zgc:173729ENSDARG00000057263Danio rerio
 SERPINB6LENSGALG00000012866Gallus gallus
 Gm11397ENSMUSG00000071452Mus musculus
 Serpinb9ENSMUSG00000045827Mus musculus
 Serpinb9bENSMUSG00000021403Mus musculus
 Serpinb9cENSMUSG00000021404Mus musculus
 Serpinb9dENSMUSG00000054266Mus musculus
 Serpinb9eENSMUSG00000062342Mus musculus
 Serpinb9fENSMUSG00000038327Mus musculus
 Serpinb9gENSMUSG00000057726Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P35237 / SERPINB6 / serpin family B member 6ENSG0000012457063
P50452 / SERPINB8 / serpin family B member 8ENSG0000016640162
P30740 / SERPINB1 / serpin family B member 1ENSG0000002135552
P48594 / SERPINB4 / serpin family B member 4ENSG0000020607347
P48595 / SERPINB10 / serpin family B member 10ENSG0000024255047
P29508 / SERPINB3 / serpin family B member 3ENSG0000005714946
P05120 / SERPINB2 / serpin family B member 2ENSG0000019763246
Q9UIV8 / SERPINB13 / serpin family B member 13ENSG0000019764144
P36952 / SERPINB5 / serpin family B member 5ENSG0000020607535


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR000240  Serpin B9/maspin
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain
 IPR036186  Serpin superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002448 mast cell mediated immunity IEP
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006955 immune response IDA
 biological_processGO:0009617 response to bacterium IDA
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0010951 negative regulation of endopeptidase activity IMP
 biological_processGO:0033668 negative regulation by symbiont of host apoptotic process IMP
 biological_processGO:0042270 protection from natural killer cell mediated cytotoxicity IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0071391 cellular response to estrogen stimulus IEP
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0002020 protease binding IPI
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030414 peptidase inhibitor activity IEA
 molecular_functionGO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process IMP


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr