ENSG00000197632


Homo sapiens

Features
Gene ID: ENSG00000197632
  
Biological name :SERPINB2
  
Synonyms : P05120 / SERPINB2 / serpin family B member 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: q21.33
Gene start: 63871692
Gene end: 63903890
  
Corresponding Affymetrix probe sets: 204614_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000385397
Ensembl peptide - ENSP00000402386
Ensembl peptide - ENSP00000401645
Ensembl peptide - ENSP00000397096
Ensembl peptide - ENSP00000299502
NCBI entrez gene - 5055     See in Manteia.
OMIM - 173390
RefSeq - NM_002575
RefSeq - NM_001143818
RefSeq Peptide - NP_001137290
RefSeq Peptide - NP_002566
swissprot - P05120
swissprot - E7ERB5
swissprot - E7EPJ9
swissprot - E9PDK7
Ensembl - ENSG00000197632
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SERPINB2ENSGALG00000019552Gallus gallus
 P12388ENSMUSG00000062345Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P30740 / SERPINB1 / serpin family B member 1ENSG0000002135546
P48595 / SERPINB10 / serpin family B member 10ENSG0000024255046
P35237 / SERPINB6 / serpin family B member 6ENSG0000012457045
P50452 / SERPINB8 / serpin family B member 8ENSG0000016640143
P50453 / SERPINB9 / serpin family B member 9ENSG0000017054242
P29508 / SERPINB3 / serpin family B member 3ENSG0000005714941
P48594 / SERPINB4 / serpin family B member 4ENSG0000020607341
Q9UIV8 / SERPINB13 / serpin family B member 13ENSG0000019764138
P36952 / SERPINB5 / serpin family B member 5ENSG0000020607531


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR015556  Plasminogen activator inhibitor-2
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain
 IPR036186  Serpin superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0035722 interleukin-12-mediated signaling pathway TAS
 biological_processGO:0042060 wound healing IEA
 biological_processGO:0042730 fibrinolysis TAS
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity TAS
 molecular_functionGO:0030414 peptidase inhibitor activity IEA


Pathways (from Reactome)
Pathway description
Dissolution of Fibrin Clot
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000122861 PLAU / P00749 / plasminogen activator, urokinase  / complex / reaction
 ENSG00000011422 PLAUR / Q03405 / plasminogen activator, urokinase receptor  / reaction / complex






 

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