ENSG00000275385


Homo sapiens

Features
Gene ID: ENSG00000275385
  
Biological name :CCL18
  
Synonyms : CCL18 / C-C motif chemokine ligand 18 / P55774
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q12
Gene start: 36064280
Gene end: 36072032
  
Corresponding Affymetrix probe sets: 209924_at (Human Genome U133 Plus 2.0 Array)   32128_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000479955
NCBI entrez gene - 6362     See in Manteia.
OMIM - 603757
RefSeq - NM_002988
RefSeq Peptide - NP_002979
swissprot - P55774
Ensembl - ENSG00000275385
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccl35.1ENSDARG00000103466Danio rerio
 ccl35.2ENSDARG00000070378Danio rerio
 ENSGALG00000041079Gallus gallus
 ENSGALG00000043065Gallus gallus
 ENSGALG00000014585Gallus gallus
 CCAH221ENSGALG00000027051Gallus gallus
 CCL4ENSGALG00000034478Gallus gallus
 CCL4ENSGALG00000032717Gallus gallus
 Ccl3ENSMUSG00000000982Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCL3L1 / CCL3L3 / P16619 / C-C motif chemokine ligand 3 like 1ENSG0000027608563
CCL3 / P10147 / C-C motif chemokine ligand 3ENSG0000027763263
CCL14 / Q16627 / C-C motif chemokine ligand 14ENSG0000027640945
CCL4 / P13236 / C-C motif chemokine ligand 4ENSG0000027530244
CCL26 / Q9Y258 / C-C motif chemokine ligand 26ENSG0000000660639
CCL5 / P13501 / C-C motif chemokine ligand 5ENSG0000027150338
CCL16 / O15467 / C-C motif chemokine ligand 16ENSG0000027515236
CCL4L2 / Q8NHW4 / C-C motif chemokine ligand 4 like 2ENSG0000027607030


Protein motifs (from Interpro)
Interpro ID Name
 IPR000827  CC chemokine, conserved site
 IPR001811  Chemokine interleukin-8-like domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002548 monocyte chemotaxis IBA
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007154 cell communication TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008009 chemokine activity TAS
 molecular_functionGO:0048020 CCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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