ENSG00000275152


Homo sapiens

Features
Gene ID: ENSG00000275152
  
Biological name :CCL16
  
Synonyms : CCL16 / C-C motif chemokine ligand 16 / O15467
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q12
Gene start: 35976493
Gene end: 35981496
  
Corresponding Affymetrix probe sets: 207354_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000478024
Ensembl peptide - ENSP00000478934
Ensembl peptide - ENSP00000478592
NCBI entrez gene - 6360     See in Manteia.
OMIM - 601394
RefSeq - NM_004590
RefSeq - XM_005258020
RefSeq Peptide - NP_004581
swissprot - A0A087WUU4
swissprot - A0A087WUE5
swissprot - O15467
Ensembl - ENSG00000275152
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ccl35.1ENSDARG00000103466Danio rerio
 ccl35.2ENSDARG00000070378Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CCL5 / P13501 / C-C motif chemokine ligand 5ENSG0000027150332
CCL14 / Q16627 / C-C motif chemokine ligand 14ENSG0000027640932
CCL4 / P13236 / C-C motif chemokine ligand 4ENSG0000027530228
CCL26 / Q9Y258 / C-C motif chemokine ligand 26ENSG0000000660628
CCL3 / P10147 / C-C motif chemokine ligand 3ENSG0000027763228
CCL3L1 / CCL3L3 / P16619 / C-C motif chemokine ligand 3 like 1ENSG0000027608528
CCL18 / P55774 / C-C motif chemokine ligand 18ENSG0000027538527
CCL4L2 / Q8NHW4 / C-C motif chemokine ligand 4 like 2ENSG0000027607018


Protein motifs (from Interpro)
Interpro ID Name
 IPR000827  CC chemokine, conserved site
 IPR001811  Chemokine interleukin-8-like domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002548 monocyte chemotaxis IBA
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007154 cell communication TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0050918 positive chemotaxis IEA
 biological_processGO:0060326 cell chemotaxis IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity TAS
 molecular_functionGO:0042056 chemoattractant activity IDA
 molecular_functionGO:0048020 CCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
Chemokine receptors bind chemokines
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000163823 CCR1 / P32246 / C-C motif chemokine receptor 1  / complex / reaction
 ENSG00000121807 CCR2 / P41597 / C-C motif chemokine receptor 2  / complex / reaction
 ENSG00000179934 CCR8 / P51685 / C-C motif chemokine receptor 8  / complex / reaction






 

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