ENSG00000278828


Homo sapiens

Features
Gene ID: ENSG00000278828
  
Biological name :HIST1H3H
  
Synonyms : HIST1H3H / histone cluster 1 H3 family member h / P68431
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p22.1
Gene start: 27810064
Gene end: 27811300
  
Corresponding Affymetrix probe sets: 206110_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000358160
NCBI entrez gene - 8357     See in Manteia.
OMIM - 602818
RefSeq - NM_003536
RefSeq Peptide - NP_003527
swissprot - P68431
Ensembl - ENSG00000278828
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P68431 / HIST1H3C / histone cluster 1 H3 family member cENSG00000278272100
P68431 / HIST1H3I / histone cluster 1 H3 family member iENSG00000275379100
P68431 / HIST1H3G / histone cluster 1 H3 family member gENSG00000273983100
P68431 / HIST1H3F / histone cluster 1 H3 family member fENSG00000277775100
P68431 / HIST1H3J / histone cluster 1 H3 family member jENSG00000197153100
P68431 / HIST1H3B / histone cluster 1 H3 family member bENSG00000274267100
P68431 / HIST1H3E / histone cluster 1 H3 family member eENSG00000274750100
P68431 / HIST1H3A / histone cluster 1 H3 family member aENSG00000275714100
P68431 / HIST1H3D / histone cluster 1 H3 family member dENSG00000197409100
Q71DI3 / HIST2H3A / histone cluster 2 H3 family member aENSG0000020385299
Q71DI3 / HIST2H3C / histone cluster 2 H3 family member cENSG0000020381199
Q71DI3 / HIST2H3D / histone cluster 2 H3 family member dENSG0000018359899
HIST2H3PS2 / histone cluster 2 H3 pseudogene 2ENSG0000020381897
Q16695 / HIST3H3 / histone cluster 3 H3ENSG0000016814897
H3F3B / P84243 / H3 histone family member 3BENSG0000013247596
H3F3A / P84243 / H3 histone family member 3AENSG0000016304196
H3F3C / Q6NXT2 / H3 histone family member 3CENSG0000018837593
H3.Y / histone cluster 2, H3c pseudogeneENSG0000026946678
P04908 / HIST1H2AE / histone cluster 1 H2A family member eENSG0000027707520
P04908 / HIST1H2AB / histone cluster 1 H2A family member bENSG0000027846320


Protein motifs (from Interpro)
Interpro ID Name
 IPR000164  Histone H3/CENP-A
 IPR007125  Histone H2A/H2B/H3
 IPR009072  Histone-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000183 chromatin silencing at rDNA TAS
 biological_processGO:0006325 chromatin organization TAS
 biological_processGO:0006334 nucleosome assembly IBA
 biological_processGO:0006335 DNA replication-dependent nucleosome assembly IDA
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0032200 telomere organization TAS
 biological_processGO:0038111 interleukin-7-mediated signaling pathway TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0045652 regulation of megakaryocyte differentiation TAS
 biological_processGO:0045814 negative regulation of gene expression, epigenetic TAS
 biological_processGO:0045815 positive regulation of gene expression, epigenetic TAS
 biological_processGO:0051290 protein heterotetramerization IDA
 biological_processGO:0060964 regulation of gene silencing by miRNA TAS
 biological_processGO:0060968 regulation of gene silencing IDA
 biological_processGO:1902036 regulation of hematopoietic stem cell differentiation TAS
 cellular_componentGO:0000228 nuclear chromosome IDA
 cellular_componentGO:0000786 nucleosome IBA
 cellular_componentGO:0000788 nuclear nucleosome IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031492 nucleosomal DNA binding IBA
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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