ENSGALG00000001143


Gallus gallus

Features
Gene ID: ENSGALG00000001143
  
Biological name :ETS1
  
Synonyms : ETS1 / protein C-ets-1
  
Possible biological names infered from orthology : ETS proto-oncogene 1, transcription factor / P14921 / P27577
  
Species: Gallus gallus
  
Chr. number: 24
Strand: -1
Band:
Gene start: 878535
Gene end: 944202
  
Corresponding Affymetrix probe sets: Gga.13782.1.S1_at (Chicken Array)   Gga.4954.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000001715
Ensembl peptide - ENSGALP00000001717
NCBI entrez gene - 396235     See in Manteia.
RefSeq - XM_015297969
RefSeq - NM_205298
RefSeq - XM_015297968
RefSeq Peptide - NP_990629
swissprot - G9LQW2
swissprot - F1P3R9
Ensembl - ENSGALG00000001143
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ets2ENSDARG00000103980Danio rerio
 ETS1ENSG00000134954Homo sapiens
 Ets1ENSMUSG00000032035Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ETS2 / P10157 / Protein C-ets-2 ENSGALG0000001605950
ERG / Q90837 / Transcriptional regulator Erg / P11308* / P81270* / ERG, ETS transcription factor*ENSGALG0000001605825
GABPA / GA binding protein transcription factor alpha subunit / Q00422* / Q06546* / GA-binding protein alpha chain *ENSGALG0000001576324
FLI1 / Friend leukemia integration 1 transcription factor / P26323* / Q01543* / Fli-1 proto-oncogene, ETS transcription factor*ENSGALG0000000116123
ETV1 / ETS variant 1 / P41164* / P50549* / ETS translocation variant 1 *ENSGALG0000003550421
ETV4 / ETS variant 4 / P28322* / P43268* / ETS translocation variant 4 *ENSGALG0000003667820
ETV5 / ETS translocation variant 5 / P41161* / Q9CXC9* / ETS variant 5*ENSGALG0000000576819
ENSGALG0000002669815
ETV3* / ETV3L* / P41162* / Q6ZN32* / Q8R4Z4* / ETS variant 3* / ETS variant 3 like* / ETS translocation variant 3 *ENSGALG0000000066913
ETV3* / ETV3L* / P41162* / Q6ZN32* / Q8R4Z4* / ETS variant 3* / ETS variant 3 like* / ETS translocation variant 3 *ENSGALG0000002713813
ELK3 / ELK3, ETS transcription factor / P41970* / P41971* / ETS domain-containing protein Elk-3 *ENSGALG0000004370111
ELK4* / P28324* / P41158* / ELK4, ETS transcription factor* / ETS domain-containing protein Elk-4 *ENSGALG0000004213711


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR003118  Pointed domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR016311  Transforming protein C-ets


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0010595 positive regulation of endothelial cell migration IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0030578 PML body organization IEA
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration IEA
 biological_processGO:0045648 positive regulation of erythrocyte differentiation IEA
 biological_processGO:0045765 regulation of angiogenesis IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048870 cell motility IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0050729 positive regulation of inflammatory response IEA
 biological_processGO:0051272 positive regulation of cellular component movement IEA
 biological_processGO:0061614 pri-miRNA transcription by RNA polymerase II IEA
 biological_processGO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000982 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:1990837 sequence-specific double-stranded DNA binding IEA


Pathways (from Reactome)
Pathway description
Oncogene Induced Senescence


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001501 MAPK1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.*  / reaction






 

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