ENSDARG00000103980


Danio rerio

Features
Gene ID: ENSDARG00000103980
  
Biological name :ets2
  
Synonyms : ets2 / v-ets avian erythroblastosis virus E26 oncogene homolog 2
  
Possible biological names infered from orthology : ETS1 / ETS proto-oncogene 1, transcription factor / P14921 / P27577 / Protein C-ets-1
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 187760
Gene end: 196815
  
Corresponding Affymetrix probe sets: Dr.7710.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000131539
Ensembl peptide - ENSDARP00000133709
NCBI entrez gene - 326672     See in Manteia.
swissprot - A0A0R4IJD6
swissprot - Q501S1
ZFIN ID - ZDB-GENE-050522-552
Ensembl - ENSDARG00000103980
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ETS1ENSGALG00000001143Gallus gallus
 ETS2ENSGALG00000016059Gallus gallus
 ETS1ENSG00000134954Homo sapiens
 Ets1ENSMUSG00000032035Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fli1a / Fli-1 proto-oncogene, ETS transcription factor a / FLI1* / P26323* / Q01543* / Fli-1 proto-oncogene, ETS transcription factor* / Friend leukemia integration 1 transcription factor *ENSDARG0000005463227
etv2 / ets variant 2 / O00321* / P41163* / ETS translocation variant 2 *ENSDARG0000005386824
gabpa / GA binding protein transcription factor, alpha subunit / Q00422* / Q06546* / GA-binding protein alpha chain *ENSDARG0000006928924
fli1b / Fli-1 proto-oncogene, ETS transcription factor bENSDARG0000004008024
erg / v-ets avian erythroblastosis virus E26 oncogene homolog / FLI1* / Q01543* / Fli-1 proto-oncogene, ETS transcription factor*ENSDARG0000007730423
CABZ01069595.1 / ELK4* / P28324* / ELK4, ETS transcription factor*ENSDARG0000002443121
etv4 / ets variant 4 / P28322* / P43268* / ETS translocation variant 4 *ENSDARG0000001830319
etv1 / ets variant 1ENSDARG0000010195919
etv5a / ets variant 5a / ETV1* / P41164* / P50549* / ETS variant 1* / ETS translocation variant 1 *ENSDARG0000006976319
etv5b / ets variant 5bENSDARG0000004451118
fev / A3FEM2 / FEV (ETS oncogene family)ENSDARG0000000924216
elk1 / ELK1, member of ETS oncogene family / P19419* / P41969* / ELK1, ETS transcription factor* / ETS domain-containing protein Elk-1 *ENSDARG0000007806614
erfl3 / Ets2 repressor factor like 3ENSDARG0000006280114
erfl1 / Ets2 repressor factor like 1 / ERF* / Gm4881* / P50548* / AC010616.1* / ETS2 repressor factor*ENSDARG0000008689214
erf / Ets2 repressor factorENSDARG0000006341714
elk4 / ELK4, ETS-domain protein / P28324* / P41158* / ELK4, ETS transcription factor* / ETS domain-containing protein Elk-4 *ENSDARG0000007709213
si:ch211-265g22.4ENSDARG0000007651212
elk3 / ELK3, ETS-domain protein / P41970* / P41971* / ELK3, ETS transcription factor* / ETS domain-containing protein Elk-3 *ENSDARG0000001868812


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR003118  Pointed domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR016311  Transforming protein C-ets


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0030154 cell differentiation IBA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
Oncogene Induced Senescence


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000027552 mapk1 / mitogen-activated protein kinase 1 / P28482* / P63085* / Mus musculus mitogen-activated protein kinase 1 (Mapk1), transcript variant 3, mRNA.*  / reaction
 ENSDARG00000070573 mapk3 / mitogen-activated protein kinase 3 / P27361* / Q63844*  / reaction






 

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