ENSDARG00000009242


Danio rerio

Features
Gene ID: ENSDARG00000009242
  
Biological name :fev
  
Synonyms : A3FEM2 / fev / FEV (ETS oncogene family)
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 11548233
Gene end: 11551608
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000107018
Ensembl peptide - ENSDARP00000087775
Ensembl peptide - ENSDARP00000145844
NCBI entrez gene - 791175     See in Manteia.
RefSeq - NM_001328149
RefSeq - XM_021478771
RefSeq Peptide - NP_001315078
swissprot - F1R323
swissprot - A3FEM2
ZFIN ID - ZDB-GENE-070112-1852
Ensembl - ENSDARG00000009242
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000026698Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fli1a / Fli-1 proto-oncogene, ETS transcription factor a / FLI1* / P26323* / Q01543* / Fli-1 proto-oncogene, ETS transcription factor* / Friend leukemia integration 1 transcription factor *ENSDARG0000005463249
fli1b / Fli-1 proto-oncogene, ETS transcription factor bENSDARG0000004008048
erg / v-ets avian erythroblastosis virus E26 oncogene homolog / FLI1* / Q01543* / Fli-1 proto-oncogene, ETS transcription factor*ENSDARG0000007730447
ets2 / v-ets avian erythroblastosis virus E26 oncogene homolog 2 / ETS1* / P14921* / P27577* / Protein C-ets-1 * / ETS proto-oncogene 1, transcription factor*ENSDARG0000010398030
etv4 / ets variant 4 / P28322* / P43268* / ETS translocation variant 4 *ENSDARG0000001830329
erfl3 / Ets2 repressor factor like 3ENSDARG0000006280129
etv1 / ets variant 1ENSDARG0000010195929
erf / Ets2 repressor factorENSDARG0000006341729
etv5b / ets variant 5bENSDARG0000004451128
gabpa / GA binding protein transcription factor, alpha subunit / Q00422* / Q06546* / GA-binding protein alpha chain *ENSDARG0000006928928
elk3 / ELK3, ETS-domain protein / P41970* / P41971* / ELK3, ETS transcription factor* / ETS domain-containing protein Elk-3 *ENSDARG0000001868828
etv2 / ets variant 2 / O00321* / P41163* / ETS translocation variant 2 *ENSDARG0000005386828
erfl1 / Ets2 repressor factor like 1 / ERF* / Gm4881* / P50548* / AC010616.1* / ETS2 repressor factor*ENSDARG0000008689228
etv5a / ets variant 5a / ETV1* / P41164* / P50549* / ETS variant 1* / ETS translocation variant 1 *ENSDARG0000006976327
elk1 / ELK1, member of ETS oncogene family / P19419* / P41969* / ELK1, ETS transcription factor* / ETS domain-containing protein Elk-1 *ENSDARG0000007806627
elk4 / ELK4, ETS-domain protein / P28324* / P41158* / ELK4, ETS transcription factor* / ETS domain-containing protein Elk-4 *ENSDARG0000007709226
si:ch211-265g22.4ENSDARG0000007651221
CABZ01069595.1 / ELK4* / P28324* / ELK4, ETS transcription factor*ENSDARG000000244313


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR011991  ArsR-like helix-turn-helix domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0060218 hematopoietic stem cell differentiation IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000014 dorsal aorta dorsal aorta decreased thickness , abnormal
dorsal aorta lacks parts or has fewer parts of type endothelial cell , abnormal
Show

 ZFA:0000033 intermediate cell mass of mesoderm intermediate cell mass of mesoderm lacks parts or has fewer parts of type hematopoietic stem cell , abnormal
Show

 ZFA:0000151 pronephros pronephros lacks parts or has fewer parts of type hematopoietic stem cell , abnormal
Show

 ZFA:0001078 thymus thymus lacks parts or has fewer parts of type T cell , abnormal
Show

 ZFA:0005028 ventral wall of dorsal aorta ventral wall of dorsal aorta apoptotic process increased process quality , abnormal
ventral wall of dorsal aorta cell proliferation decreased process quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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