ENSDARG00000054632


Danio rerio

Features
Gene ID: ENSDARG00000054632
  
Biological name :fli1a
  
Synonyms : fli1a / Fli-1 proto-oncogene, ETS transcription factor a
  
Possible biological names infered from orthology : FLI1 / Fli-1 proto-oncogene, ETS transcription factor / Friend leukemia integration 1 transcription factor / P26323 / Q01543
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 48423973
Gene end: 48487875
  
Corresponding Affymetrix probe sets: Dr.26421.1.A1_at (Zebrafish Array)   Dr.8126.1.S1_at (Zebrafish Array)   NM_131348_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000071331
Ensembl peptide - ENSDARP00000112877
Ensembl peptide - ENSDARP00000115341
Ensembl peptide - ENSDARP00000117852
Ensembl peptide - ENSDARP00000151205
NCBI entrez gene - 30619     See in Manteia.
RefSeq - XM_021467585
RefSeq - NM_131348
RefSeq - XM_021467584
RefSeq Peptide - NP_571423
swissprot - Q1L8J3
swissprot - Q9PU61
swissprot - Q1L8J1
swissprot - Q1L8J0
ZFIN ID - ZDB-GENE-980526-426
Ensembl - ENSDARG00000054632
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FLI1ENSGALG00000001161Gallus gallus
 FLI1ENSG00000151702Homo sapiens
 Fli1ENSMUSG00000016087Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fli1b / Fli-1 proto-oncogene, ETS transcription factor bENSDARG0000004008054
erg / v-ets avian erythroblastosis virus E26 oncogene homolog / FLI1* / Q01543* / Fli-1 proto-oncogene, ETS transcription factor*ENSDARG0000007730452
ets2 / v-ets avian erythroblastosis virus E26 oncogene homolog 2 / ETS1* / P14921* / P27577* / Protein C-ets-1 * / ETS proto-oncogene 1, transcription factor*ENSDARG0000010398027
fev / A3FEM2 / FEV (ETS oncogene family)ENSDARG0000000924225
gabpa / GA binding protein transcription factor, alpha subunit / Q00422* / Q06546* / GA-binding protein alpha chain *ENSDARG0000006928923
etv5b / ets variant 5bENSDARG0000004451119
etv4 / ets variant 4 / P28322* / P43268* / ETS translocation variant 4 *ENSDARG0000001830319
etv5a / ets variant 5a / ETV1* / P41164* / P50549* / ETS variant 1* / ETS translocation variant 1 *ENSDARG0000006976319
erf / Ets2 repressor factorENSDARG0000006341718
etv2 / ets variant 2 / O00321* / P41163* / ETS translocation variant 2 *ENSDARG0000005386818
etv1 / ets variant 1ENSDARG0000010195918
erfl3 / Ets2 repressor factor like 3ENSDARG0000006280117
erfl1 / Ets2 repressor factor like 1 / ERF* / Gm4881* / P50548* / AC010616.1* / ETS2 repressor factor*ENSDARG0000008689215
elk3 / ELK3, ETS-domain protein / P41970* / P41971* / ELK3, ETS transcription factor* / ETS domain-containing protein Elk-3 *ENSDARG0000001868814
elk1 / ELK1, member of ETS oncogene family / P19419* / P41969* / ELK1, ETS transcription factor* / ETS domain-containing protein Elk-1 *ENSDARG0000007806614
elk4 / ELK4, ETS-domain protein / P28324* / P41158* / ELK4, ETS transcription factor* / ETS domain-containing protein Elk-4 *ENSDARG0000007709213
si:ch211-265g22.4ENSDARG0000007651212
CABZ01069595.1 / ELK4* / P28324* / ELK4, ETS transcription factor*ENSDARG0000002443110


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR003118  Pointed domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR035573  Friend leukemia integration 1 transcription factor, pointed domain
 IPR035575  Friend leukemia integration 1 transcription factor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IGI
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0048514 blood vessel morphogenesis IGI
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001114 head head hemorrhagic , abnormal
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 ZFA:0001267 cranial vasculature cranial vasculature hemorrhagic , abnormal
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 ZFA:0001285 intersegmental vessel intersegmental vessel decreased amount , abnormal
intersegmental vessel irregular spatial pattern , abnormal
intersegmental vessel disorganized , abnormal
intersegmental vessel aplastic , abnormal
Show

 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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