ENSGALG00000015763


Gallus gallus

Features
Gene ID: ENSGALG00000015763
  
Biological name :GABPA
  
Synonyms : GA binding protein transcription factor alpha subunit / GABPA
  
Possible biological names infered from orthology : GA-binding protein alpha chain / Q00422 / Q06546
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 102548449
Gene end: 102578189
  
Corresponding Affymetrix probe sets: Gga.13581.1.S1_s_at (Chicken Array)   Gga.18967.1.S1_s_at (Chicken Array)   GgaAffx.12691.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000025373
NCBI entrez gene - 418478     See in Manteia.
RefSeq - XM_015299140
RefSeq - NM_001007858
RefSeq - XM_015299146
RefSeq Peptide - NP_001007859
swissprot - Q5ZJ46
Ensembl - ENSGALG00000015763
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gabpaENSDARG00000069289Danio rerio
 GABPAENSG00000154727Homo sapiens
 GabpaENSMUSG00000008976Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ETS2 / P10157 / Protein C-ets-2 ENSGALG0000001605927
ETS1 / protein C-ets-1 / P14921* / P27577* / ETS proto-oncogene 1, transcription factor*ENSGALG0000000114326
ERG / Q90837 / Transcriptional regulator Erg / P11308* / P81270* / ERG, ETS transcription factor*ENSGALG0000001605825
FLI1 / Friend leukemia integration 1 transcription factor / P26323* / Q01543* / Fli-1 proto-oncogene, ETS transcription factor*ENSGALG0000000116124
ETV4 / ETS variant 4 / P28322* / P43268* / ETS translocation variant 4 *ENSGALG0000003667818
ETV5 / ETS translocation variant 5 / P41161* / Q9CXC9* / ETS variant 5*ENSGALG0000000576817
ETV1 / ETS variant 1 / P41164* / P50549* / ETS translocation variant 1 *ENSGALG0000003550417
ENSGALG0000002669816
ELK3 / ELK3, ETS transcription factor / P41970* / P41971* / ETS domain-containing protein Elk-3 *ENSGALG0000004370113
ELK4* / P28324* / P41158* / ELK4, ETS transcription factor* / ETS domain-containing protein Elk-4 *ENSGALG0000004213713
ETV3* / ETV3L* / P41162* / Q6ZN32* / Q8R4Z4* / ETS variant 3* / ETS variant 3 like* / ETS translocation variant 3 *ENSGALG0000000066913
ETV3* / ETV3L* / P41162* / Q6ZN32* / Q8R4Z4* / ETS variant 3* / ETS variant 3 like* / ETS translocation variant 3 *ENSGALG0000002713812


Protein motifs (from Interpro)
Interpro ID Name
 IPR000418  Ets domain
 IPR003118  Pointed domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR013761  Sterile alpha motif/pointed domain superfamily
 IPR016312  Transcription factor, GA-binding, alpha subunit
 IPR024668  GA-binding protein alpha subunit, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0045653 negative regulation of megakaryocyte differentiation IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:1903351 cellular response to dopamine IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0033613 activating transcription factor binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Transcriptional activation of mitochondrial biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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