ENSGALG00000002247


Gallus gallus

Features
Gene ID: ENSGALG00000002247
  
Biological name :SETD6
  
Synonyms : SETD6 / SET domain containing 6
  
Possible biological names infered from orthology : N-lysine methyltransferase SETD6 / Q8TBK2 / Q9CWY3
  
Species: Gallus gallus
  
Chr. number: 11
Strand: 1
Band:
Gene start: 1466697
Gene end: 1470782
  
Corresponding Affymetrix probe sets: Gga.4335.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000003512
NCBI entrez gene - 101750922     See in Manteia.
RefSeq - NM_001030563
RefSeq Peptide - NP_001025734
swissprot - F1P3Z2
Ensembl - ENSGALG00000002247
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 setd6ENSDARG00000043986Danio rerio
 SETD6ENSG00000103037Homo sapiens
 Setd6ENSMUSG00000031671Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR011383  N-lysine methyltransferase SETD6
 IPR015353  Rubisco LSMT, substrate-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0018026 peptidyl-lysine monomethylation IEA
 biological_processGO:0019827 stem cell population maintenance IEA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0034968 histone lysine methylation IEA
 biological_processGO:0048863 stem cell differentiation IEA
 biological_processGO:0050727 regulation of inflammatory response IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0016279 protein-lysine N-methyltransferase activity IEA
 molecular_functionGO:0051059 NF-kappaB binding IEA


Pathways (from Reactome)
Pathway description
PKMTs methylate histone lysines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000012304 NFKB1 / Q04861 / Nuclear factor NF-kappa-B p105 subunit Nuclear factor NF-kappa-B p50 subunit / P19838* / P25799* / nuclear factor kappa B subunit 1*  / reaction






 

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contact: otassy@igbmc.fr