ENSGALG00000002389


Gallus gallus

Features
Gene ID: ENSGALG00000002389
  
Biological name :ITGB4
  
Synonyms : integrin subunit beta 4 / ITGB4
  
Possible biological names infered from orthology : A2A863 / Integrin beta-4 / P16144
  
Species: Gallus gallus
  
Chr. number: 18
Strand: -1
Band:
Gene start: 4776921
Gene end: 4798548
  
Corresponding Affymetrix probe sets: Gga.6814.1.S1_s_at (Chicken Array)   GgaAffx.1589.1.S1_s_at (Chicken Array)   GgaAffx.25470.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000003752
Ensembl peptide - ENSGALP00000052160
Ensembl peptide - ENSGALP00000046793
Ensembl peptide - ENSGALP00000043497
NCBI entrez gene - 417374     See in Manteia.
RefSeq - XM_015295328
RefSeq - XM_015295323
RefSeq - XM_015295325
RefSeq - XM_015295326
RefSeq - XM_015295327
swissprot - A0A1D5PH83
swissprot - A0A1D5P298
swissprot - A0A1D5NT44
swissprot - E1C9G7
Ensembl - ENSGALG00000002389
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itgb4ENSDARG00000028507Danio rerio
 ITGB4ENSG00000132470Homo sapiens
 Itgb4ENSMUSG00000020758Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ITGB6 / integrin subunit beta 6 / P18564* / Q9Z0T9* / Integrin beta-6 *ENSGALG0000001114115
ITGB2 / integrin beta-2 precursor / Itgb2l* / P05107* / Q3UV74* / integrin subunit beta 2* / Integrin beta-2-like protein *ENSGALG0000000751115
ITGB1 / integrin subunit beta 1 / P05556* / P09055* / Integrin beta-1 *ENSGALG0000000714515
ITGB3 / P05106* / O54890* / AC068234.1* / Integrin beta-3 * / integrin subunit beta 3*ENSGALG0000000037915
ITGB5 / integrin beta-5 precursor / P18084* / integrin subunit beta 5*ENSGALG0000002976615
ITGB8 / integrin subunit beta 8 / P26012*ENSGALG0000001087512
ITGBL1 / integrin subunit beta like 1 / O95965* / Q8VDV0* / Integrin beta-like protein 1 *ENSGALG000000168676


Protein motifs (from Interpro)
Interpro ID Name
 IPR002035  von Willebrand factor, type A
 IPR002369  Integrin beta subunit, VWA domain
 IPR003644  Na-Ca exchanger/integrin-beta4
 IPR003961  Fibronectin type III
 IPR012013  Integrin beta-4 subunit
 IPR012896  Integrin beta subunit, tail
 IPR013032  EGF-like, conserved site
 IPR013783  Immunoglobulin-like fold
 IPR015812  Integrin beta subunit
 IPR033760  Integrin beta N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0007154 cell communication IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007229 integrin-mediated signaling pathway IEA
 biological_processGO:0009611 response to wounding IEA
 biological_processGO:0031581 hemidesmosome assembly IEA
 biological_processGO:0035878 nail development IEA
 biological_processGO:0043588 skin development IEA
 biological_processGO:0048333 mesodermal cell differentiation IEA
 biological_processGO:0048565 digestive tract development IEA
 biological_processGO:0048870 cell motility IEA
 biological_processGO:0072001 renal system development IEA
 biological_processGO:0097186 amelogenesis IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008305 integrin complex IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030056 hemidesmosome IEA
 cellular_componentGO:0031252 cell leading edge IEA
 cellular_componentGO:0043235 receptor complex IEA
 molecular_functionGO:0001664 G-protein coupled receptor binding IEA
 molecular_functionGO:0031994 insulin-like growth factor I binding IEA
 molecular_functionGO:0038132 neuregulin binding IEA


Pathways (from Reactome)
Pathway description
Laminin interactions
Syndecan interactions
Type I hemidesmosome assembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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