ENSGALG00000002507


Gallus gallus

Features
Gene ID: ENSGALG00000002507
  
Biological name :MBL2
  
Synonyms : Mannose-binding protein / MBL2 / Q98TA4
  
Possible biological names infered from orthology : mannose binding lectin 2 / mannose-binding lectin (protein C) 2 / Mannose-binding protein A / Mbl1 / P11226 / P39039 / P41317
  
Species: Gallus gallus
  
Chr. number: 6
Strand: -1
Band:
Gene start: 4503081
Gene end: 4511262
  
Corresponding Affymetrix probe sets: Gga.174.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000040351
NCBI entrez gene - 374267     See in Manteia.
RefSeq - XM_015287952
RefSeq - NM_204349
RefSeq - XM_015287953
RefSeq Peptide - NP_989680
swissprot - Q98TA4
Ensembl - ENSGALG00000002507
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hbl1ENSDARG00000068221Danio rerio
 hbl2ENSDARG00000094681Danio rerio
 hbl4ENSDARG00000054202Danio rerio
 mbl2ENSDARG00000068220Danio rerio
 MBL2ENSG00000165471Homo sapiens
 Mbl1ENSMUSG00000037780Mus musculus
 Mbl2ENSMUSG00000024863Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q2LK95 / COLEC10 / Collectin-10 / Q8CF98* / Q9Y6Z7* / collectin subfamily member 10*ENSGALG0000003314430
COLEC11 / collectin-11 precursor / Q9BWP8* / collectin subfamily member 11*ENSGALG0000003730929
SFTPA2 / Q8IWL2* / SFTPA1* / Q8IWL1* / surfactant protein A1* / surfactant protein A2* / surfactant associated protein A1*ENSGALG0000000250322
SFTPA1 / Q8IWL2* / SFTPA2* / Q8IWL1* / surfactant protein A1* / surfactant protein A2* / surfactant associated protein A1*ENSGALG0000000249620


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR008160  Collagen triple helix repeat
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001867 complement activation, lectin pathway TAS
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006956 complement activation TAS
 biological_processGO:0006958 complement activation, classical pathway IEA
 biological_processGO:0045087 innate immune response IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005581 collagen trimer IEA
 molecular_functionGO:0005537 mannose binding IEA
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
Lectin pathway of complement activation
Initial triggering of complement
Creation of classical C3 convertase
Lectin-mediated initiation of complement cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000007419 MASP1 / mannan-binding lectin serine protease 1 precursor / P48740* / P98064* / mannan binding lectin serine peptidase 1* / Mus musculus mannan-binding lectin serine peptidase 1 (Masp1), t...  / complex
 ENSGALG00000002507 MBL2 / Q98TA4 / Mannose-binding protein / Mbl1* / P11226* / P39039* / P41317* / mannose binding lectin 2* / Mannose-binding protein A * / mannose-binding lectin (protein C) 2*  / complex






 

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