ENSDARG00000068220


Danio rerio

Features
Gene ID: ENSDARG00000068220
  
Biological name :mbl2
  
Synonyms : mannose binding lectin 2 / mbl2
  
Possible biological names infered from orthology : mannose-binding lectin (protein C) 2 / Mannose-binding protein A / Mbl1 / P11226 / P35247 / P39039 / P41317 / P50404 / Pulmonary surfactant-associated protein D / Q8IWL1 / Q8IWL2 / SFTPA1 / SFTPA2 / SFTPD / surfactant associated protein A1 / surfactant protein A1 / surfactant protein A2 / surfactant protein D
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 37887277
Gene end: 37889152
  
Corresponding Affymetrix probe sets: Dr.8238.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000089300
Ensembl peptide - ENSDARP00000139226
Ensembl peptide - ENSDARP00000157393
NCBI entrez gene - 100008009     See in Manteia.
RefSeq - NM_131570
RefSeq - XM_005171258
RefSeq Peptide - NP_571645
swissprot - Q504I3
ZFIN ID - ZDB-GENE-000427-2
Ensembl - ENSDARG00000068220
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MBL2ENSGALG00000002507Gallus gallus
 SFTPA1ENSGALG00000002496Gallus gallus
 SFTPA2ENSGALG00000002503Gallus gallus
 MBL2ENSG00000165471Homo sapiens
 Q8IWL1ENSG00000185303Homo sapiens
 Q8IWL2ENSG00000122852Homo sapiens
 SFTPDENSG00000133661Homo sapiens
 Mbl1ENSMUSG00000037780Mus musculus
 Mbl2ENSMUSG00000024863Mus musculus
 Sftpa1ENSMUSG00000021789Mus musculus
 SftpdENSMUSG00000021795Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hbl1 / zmp:0000000729 / hexose-binding lectin 1 / MBL2* / Mbl1* / SFTPD* / P41317* / P11226* / P35247* / P39039* / Q8IWL2* / SFTPA1* / SFTPA2* / P50404* / Q8IWL1* / surfactant protein D* / ...ENSDARG0000006822169
hbl2 / hexose-binding lectin 2 / Mbl1* / MBL2* / SFTPD* / P41317* / P11226* / P35247* / P39039* / P50404* / Q8IWL1* / Q8IWL2* / SFTPA1* / SFTPA2* / surfactant protein D* / surfactant protei...ENSDARG0000009468165
hbl4 / hexose-binding lectin 4 / Mbl1* / MBL2* / SFTPD* / P41317* / P11226* / P35247* / P39039* / P50404* / Q8IWL1* / Q8IWL2* / SFTPA1* / SFTPA2* / surfactant protein D* / surfactant protei...ENSDARG0000005420246
colec11 / collectin sub-family member 11 / Q9BWP8* / collectin subfamily member 11*ENSDARG0000001326628
COLEC10 / si:ch211-93i7.4 / Q8CF98* / Q9Y6Z7* / Collectin-10 * / collectin subfamily member 10*ENSDARG0000010475223


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR008160  Collagen triple helix repeat
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site
 IPR033990  Collectin, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001867 complement activation, lectin pathway IEA
 cellular_componentGO:0005581 collagen trimer IEA
 molecular_functionGO:0005537 mannose binding IEA
 molecular_functionGO:0030246 carbohydrate binding IBA


Pathways (from Reactome)
Pathway description
Lectin pathway of complement activation
Initial triggering of complement
Surfactant metabolism
Regulation of TLR by endogenous ligand


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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