ENSGALG00000003045


Gallus gallus

Features
Gene ID: ENSGALG00000003045
  
Biological name :E2F1
  
Synonyms : E2F1 / transcription factor E2F1
  
Possible biological names infered from orthology : E2F transcription factor 1 / Q01094 / Q61501
  
Species: Gallus gallus
  
Chr. number: 20
Strand: 1
Band:
Gene start: 2252980
Gene end: 2259130
  
Corresponding Affymetrix probe sets: Gga.3213.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004806
Ensembl peptide - ENSGALP00000042464
NCBI entrez gene - 396142     See in Manteia.
RefSeq - XM_015296338
RefSeq - NM_205219
RefSeq Peptide - NP_990550
swissprot - R4GJY3
swissprot - F1NC04
Ensembl - ENSGALG00000003045
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 e2f1ENSDARG00000103868Danio rerio
 E2F1ENSG00000101412Homo sapiens
 E2f1ENSMUSG00000027490Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
E2F3 / E2F transcription factor 3 / O00716* / O35261* / Transcription factor E2F3 *ENSGALG0000001268041
E2F4 / E2F transcription factor 4 / Q16254* / Q8R0K9* / Transcription factor E2F4 *ENSGALG0000000172225
E2F6 / E2F transcription factor 6 / O54917* / O75461* / Transcription factor E2F6 *ENSGALG0000001645425
E2F5 / transcription factor E2F5 / Q15329* / Q61502* / E2F transcription factor 5*ENSGALG0000003891524


Protein motifs (from Interpro)
Interpro ID Name
 IPR003316  E2F/DP family, winged-helix DNA-binding domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR015633  E2F Family
 IPR032198  E2F transcription factor, CC-MB domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint IEA
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0030900 forebrain development IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043276 anoikis IEA
 biological_processGO:0043392 negative regulation of DNA binding IEA
 biological_processGO:0045599 negative regulation of fat cell differentiation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048146 positive regulation of fibroblast proliferation IEA
 biological_processGO:0048255 mRNA stabilization IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:0070345 negative regulation of fat cell proliferation IEA
 biological_processGO:0071466 cellular response to xenobiotic stimulus IEA
 biological_processGO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle IEA
 biological_processGO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator IEA
 biological_processGO:1990086 lens fiber cell apoptotic process IEA
 biological_processGO:2000045 regulation of G1/S transition of mitotic cell cycle IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0035189 Rb-E2F complex IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IEA
 molecular_functionGO:0001047 core promoter binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
CDC6 association with the ORC:origin complex
G2 Phase
Cyclin D associated events in G1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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