ENSGALG00000012680


Gallus gallus

Features
Gene ID: ENSGALG00000012680
  
Biological name :E2F3
  
Synonyms : E2F3 / E2F transcription factor 3
  
Possible biological names infered from orthology : O00716 / O35261 / Transcription factor E2F3
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 59627689
Gene end: 59669274
  
Corresponding Affymetrix probe sets: GgaAffx.8032.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044105
Ensembl peptide - ENSGALP00000036527
NCBI entrez gene - 420824     See in Manteia.
RefSeq - XM_015275950
RefSeq - XM_015275948
RefSeq - XM_015275949
swissprot - F1NR90
swissprot - A0A1D5NUT7
Ensembl - ENSGALG00000012680
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 e2f3ENSDARG00000070463Danio rerio
 E2F3ENSG00000112242Homo sapiens
 E2f3ENSMUSG00000016477Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
E2F1 / transcription factor E2F1 / Q01094* / Q61501* / E2F transcription factor 1*ENSGALG0000000304538
E2F6 / E2F transcription factor 6 / O54917* / O75461* / Transcription factor E2F6 *ENSGALG0000001645425
E2F4 / E2F transcription factor 4 / Q16254* / Q8R0K9* / Transcription factor E2F4 *ENSGALG0000000172224
E2F5 / transcription factor E2F5 / Q15329* / Q61502* / E2F transcription factor 5*ENSGALG0000003891523


Protein motifs (from Interpro)
Interpro ID Name
 IPR003316  E2F/DP family, winged-helix DNA-binding domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR015633  E2F Family
 IPR032198  E2F transcription factor, CC-MB domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0070345 negative regulation of fat cell proliferation IEA
 biological_processGO:1905461 positive regulation of vascular associated smooth muscle cell apoptotic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IEA
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0001047 core promoter binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
CDC6 association with the ORC:origin complex
G2 Phase
Cyclin D associated events in G1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000016823 TFDP1* / TFDP3* / Q5H9I0* / Q08639* / Q14186* / transcription factor Dp-1* / transcription factor Dp family member 3*  / complex
 ENSGALG00000025759 TFDP2 / transcription factor Dp-2 / Q14188*  / complex






 

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