ENSGALG00000003521


Gallus gallus

Features
Gene ID: ENSGALG00000003521
  
Biological name :TPM1
  
Synonyms : P04268 / TPM1 / Tropomyosin alpha-1 chain
  
Possible biological names infered from orthology : P09493 / P58771 / tropomyosin 1 / tropomyosin 1, alpha
  
Species: Gallus gallus
  
Chr. number: 10
Strand: -1
Band:
Gene start: 4105084
Gene end: 4124081
  
Corresponding Affymetrix probe sets: Gga.4108.1.S1_at (Chicken Array)   Gga.4108.1.S2_at (Chicken Array)   Gga.4108.2.S1_a_at (Chicken Array)   Gga.4108.4.S1_a_at (Chicken Array)   Gga.4108.4.S1_s_at (Chicken Array)   Gga.4108.4.S1_x_at (Chicken Array)   Gga.4108.5.S1_x_at (Chicken Array)   GgaAffx.20738.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044392
Ensembl peptide - ENSGALP00000047096
Ensembl peptide - ENSGALP00000064071
Ensembl peptide - ENSGALP00000063109
Ensembl peptide - ENSGALP00000062806
Ensembl peptide - ENSGALP00000062356
Ensembl peptide - ENSGALP00000059327
Ensembl peptide - ENSGALP00000056013
Ensembl peptide - ENSGALP00000051797
Ensembl peptide - ENSGALP00000005562
Ensembl peptide - ENSGALP00000006384
Ensembl peptide - ENSGALP00000038799
NCBI entrez gene - 396366     See in Manteia.
RefSeq - XM_015278793
RefSeq - XM_015278781
RefSeq - XM_015278782
RefSeq - XM_015278783
RefSeq - XM_015278784
RefSeq - XM_015278785
RefSeq - XM_015278786
RefSeq - XM_015278787
RefSeq - XM_015278788
RefSeq - XM_015278789
RefSeq - XM_015278790
RefSeq - XM_015278791
RefSeq - XM_015278792
RefSeq - NM_205401
RefSeq - XM_015278774
RefSeq - XM_015278777
RefSeq - XM_015278778
RefSeq - XM_015278779
RefSeq - XM_015278780
RefSeq Peptide - NP_990732
swissprot - A0A1L1RW88
swissprot - A0A1L1RVF2
swissprot - A0A1L1RU52
swissprot - A0A1L1RKQ2
swissprot - A0A1D5PSX3
swissprot - A0A1D5P342
swissprot - F1NM23
swissprot - A0A1D5NVL7
swissprot - P04268
swissprot - A0A1L1RYZ7
swissprot - Q8AWI4
Ensembl - ENSGALG00000003521
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tpmaENSDARG00000033683Danio rerio
 zgc:171719ENSDARG00000087402Danio rerio
 TPM1ENSG00000140416Homo sapiens
 Tpm1ENSMUSG00000032366Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TPM3 / Gallus gallus tropomyosin 3 (TPM3), transcript variant 3, mRNA. / P06753* / tropomyosin 3*ENSGALG0000001353776
TPM2 / P19352 / Tropomyosin beta chain / P58774* / P07951* / tropomyosin 2* / tropomyosin 2, beta*ENSGALG0000002584270
TPM4 / tropomyosin 4 / P67936* / Q6IRU2* / Tropomyosin alpha-4 chain *ENSGALG0000000256353


Protein motifs (from Interpro)
Interpro ID Name
 IPR000533  Tropomyosin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0003065 positive regulation of heart rate by epinephrine IEA
 biological_processGO:0007015 actin filament organization IBA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0034614 cellular response to reactive oxygen species IEA
 biological_processGO:0045214 sarcomere organization IEA
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis IEA
 biological_processGO:0060048 cardiac muscle contraction IEA
 biological_processGO:1904706 negative regulation of vascular smooth muscle cell proliferation IEA
 biological_processGO:1904753 negative regulation of vascular associated smooth muscle cell migration IEA
 cellular_componentGO:0001725 stress fiber IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005862 muscle thin filament tropomyosin IBA
 cellular_componentGO:0005884 actin filament IBA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0030016 myofibril IEA
 cellular_componentGO:0031941 filamentous actin IEA
 cellular_componentGO:0032059 bleb IEA
 cellular_componentGO:0032587 ruffle membrane IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008092 cytoskeletal protein binding IEA
 molecular_functionGO:0008307 structural constituent of muscle IBA
 molecular_functionGO:0042802 identical protein binding ISS
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0046982 protein heterodimerization activity ISS
 molecular_functionGO:0051015 actin filament binding IBA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction
Smooth Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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