ENSGALG00000003675


Gallus gallus

Features
Gene ID: ENSGALG00000003675
  
Biological name :PRKAR1B
  
Synonyms : PRKAR1B / protein kinase cAMP-dependent type I regulatory subunit beta
  
Possible biological names infered from orthology : P12849 / P31321 / protein kinase, cAMP dependent regulatory, type I beta
  
Species: Gallus gallus
  
Chr. number: 14
Strand: -1
Band:
Gene start: 2034750
Gene end: 2121330
  
Corresponding Affymetrix probe sets: Gga.9736.1.S1_at (Chicken Array)   GgaAffx.25936.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005814
Ensembl peptide - ENSGALP00000059638
Ensembl peptide - ENSGALP00000050473
NCBI entrez gene - 416446     See in Manteia.
RefSeq - XM_004945114
RefSeq - XM_414754
swissprot - E1C2U6
swissprot - A0A1L1RLL4
swissprot - A0A1D5PCI4
Ensembl - ENSGALG00000003675
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prkar1bENSDARG00000103800Danio rerio
 P31321ENSG00000188191Homo sapiens
 P12849ENSMUSG00000025855Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5ZM91 / PRKAR1A / cAMP-dependent protein kinase type I-alpha regulatory subunit / Q9DBC7* / P10644* / protein kinase, cAMP dependent regulatory, type I, alpha* / protein kinase cAMP-depen...ENSGALG0000000423778
PRKAR2B / protein kinase cAMP-dependent type II regulatory subunit beta / P31323* / P31324* / protein kinase, cAMP dependent regulatory, type II beta*ENSGALG0000000806033
PRKAR2A / protein kinase cAMP-dependent type II regulatory subunit alpha / P13861* / protein kinase, cAMP dependent regulatory, type II alpha*ENSGALG0000000702331


Protein motifs (from Interpro)
Interpro ID Name
 IPR000595  Cyclic nucleotide-binding domain
 IPR003117  cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain
 IPR012198  cAMP-dependent protein kinase regulatory subunit
 IPR014710  RmlC-like jelly roll fold
 IPR018488  Cyclic nucleotide-binding, conserved site
 IPR018490  Cyclic nucleotide-binding-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001932 regulation of protein phosphorylation IEA
 biological_processGO:0007611 learning or memory IEA
 biological_processGO:0045859 regulation of protein kinase activity IEA
 biological_processGO:2000480 negative regulation of cAMP-dependent protein kinase activity IEA
 cellular_componentGO:0005952 cAMP-dependent protein kinase complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004862 cAMP-dependent protein kinase inhibitor activity IEA
 molecular_functionGO:0008603 cAMP-dependent protein kinase regulator activity IEA
 molecular_functionGO:0030552 cAMP binding IEA
 molecular_functionGO:0034236 protein kinase A catalytic subunit binding IEA


Pathways (from Reactome)
Pathway description
PKA activation
PKA activation in glucagon signalling
DARPP-32 events
Vasopressin regulates renal water homeostasis via Aquaporins
Hedgehog off state
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000005575 AKAP1 / A-kinase anchoring protein 1 / O08715* / Q92667* / A-kinase anchor protein 1, mitochondrial *  / complex / reaction
 ENSGALG00000003675 PRKAR1B / protein kinase cAMP-dependent type I regulatory subunit beta / P12849* / P31321* / protein kinase, cAMP dependent regulatory, type I beta*  / complex
 ENSGALG00000004237 Q5ZM91 / PRKAR1A / cAMP-dependent protein kinase type I-alpha regulatory subunit / Q9DBC7* / P10644* / protein kinase, cAMP dependent regulatory, type I, alpha* / protein kinase cAMP-depen...  / complex
 ENSGALG00000007023 PRKAR2A / protein kinase cAMP-dependent type II regulatory subunit alpha / P13861* / protein kinase, cAMP dependent regulatory, type II alpha*  / complex






 

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