ENSGALG00000005481


Gallus gallus

Features
Gene ID: ENSGALG00000005481
  
Biological name :ARHGEF3
  
Synonyms : ARHGEF3 / rho guanine nucleotide exchange factor 3
  
Possible biological names infered from orthology : Q91X46 / Q9NR81
  
Species: Gallus gallus
  
Chr. number: 12
Strand: -1
Band:
Gene start: 8432702
Gene end: 8463996
  
Corresponding Affymetrix probe sets: GgaAffx.11713.1.S1_s_at (Chicken Array)   GgaAffx.3442.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000008791
NCBI entrez gene - 416000     See in Manteia.
RefSeq - XM_015293070
RefSeq - NM_001030595
RefSeq - XM_015293068
RefSeq - XM_015293069
RefSeq Peptide - NP_001025766
swissprot - F1P5U0
Ensembl - ENSGALG00000005481
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgef3ENSDARG00000013834Danio rerio
 Q9NR81ENSG00000163947Homo sapiens
 Q91X46ENSMUSG00000021895Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NET1 / neuroepithelial cell transforming 1 / Q7Z628* / Q9Z206* / neuroepithelial cell transforming gene 1*ENSGALG0000000843756
ARHGEF12 / Rho guanine nucleotide exchange factor 12 / Q8R4H2* / Q9NZN5* / Mus musculus Rho guanine nucleotide exchange factor (GEF) 12 (Arhgef12), transcript variant 2, mRNA.*ENSGALG0000000666320
ARHGEF11 / Rho guanine nucleotide exchange factor 11 / O15085* / Rho guanine nucleotide exchange factor (GEF) 11*ENSGALG0000003916318
ARHGEF28 / Rho guanine nucleotide exchange factor 28 / Q8N1W1*ENSGALG0000001492318
AKAP13 / A-kinase anchoring protein 13 / E9Q394* / Q12802* / A-kinase anchor protein 13 *ENSGALG0000000684017
Q6P9R4* / Q6ZSZ5* / ARHGEF18* / AC008878.3* / Rho guanine nucleotide exchange factor 18 * / Rho/Rac guanine nucleotide exchange factor 18*ENSGALG0000000357217
ENSGALG0000002646015


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001331  Guanine-nucleotide dissociation stimulator, CDC24, conserved site
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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