ENSGALG00000014923


Gallus gallus

Features
Gene ID: ENSGALG00000014923
  
Biological name :ARHGEF28
  
Synonyms : ARHGEF28 / Rho guanine nucleotide exchange factor 28
  
Possible biological names infered from orthology : Q8N1W1
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 24570223
Gene end: 24702341
  
Corresponding Affymetrix probe sets: GgaAffx.9472.1.S1_at (Chicken Array)   GgaAffx.9478.1.S1_at (Chicken Array)   GgaAffx.9478.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000024023
Ensembl peptide - ENSGALP00000049098
NCBI entrez gene - 427201     See in Manteia.
RefSeq - XM_015277655
RefSeq - XM_015277657
RefSeq - XM_015277658
RefSeq - XM_015277659
swissprot - E1C4L8
swissprot - A0A1D5P8P9
Ensembl - ENSGALG00000014923
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arhgef28ENSDARG00000060415Danio rerio
 si:ch211-272b8.6ENSDARG00000091607Danio rerio
 Q8N1W1ENSG00000214944Homo sapiens
 Arhgef28ENSMUSG00000021662Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6P9R4* / Q6ZSZ5* / ARHGEF18* / AC008878.3* / Rho guanine nucleotide exchange factor 18 * / Rho/Rac guanine nucleotide exchange factor 18*ENSGALG0000000357224
AKAP13 / A-kinase anchoring protein 13 / E9Q394* / Q12802* / A-kinase anchor protein 13 *ENSGALG0000000684021
ARHGEF12 / Rho guanine nucleotide exchange factor 12 / Q8R4H2* / Q9NZN5* / Mus musculus Rho guanine nucleotide exchange factor (GEF) 12 (Arhgef12), transcript variant 2, mRNA.*ENSGALG0000000666314
ARHGEF11 / Rho guanine nucleotide exchange factor 11 / O15085* / Rho guanine nucleotide exchange factor (GEF) 11*ENSGALG0000003916313
NET1 / neuroepithelial cell transforming 1 / Q7Z628* / Q9Z206* / neuroepithelial cell transforming gene 1*ENSGALG000000084376
ARHGEF3 / rho guanine nucleotide exchange factor 3 / Q91X46* / Q9NR81*ENSGALG000000054815
ENSGALG000000264605


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001849  Pleckstrin homology domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR011993  PH-like domain superfamily
 IPR020683  Ankyrin repeat-containing domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
EPHB-mediated forward signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004741 EPHB2 / EPH receptor B2 / P29323* / P54763* / Ephrin type-B receptor 2 *  / complex / reaction
 ENSGALG00000006609 EPHB1 / EPH receptor B1 / P54762* / Q8CBF3* / Ephrin type-B receptor 1 *  / complex / reaction
 ENSGALG00000029175 EFNB2 / ephrin B2 / P52799* / P52800*  / complex / reaction
 ENSGALG00000031741 PTK2 / Q00944 / Focal adhesion kinase 1 / P34152* / Q05397* / protein tyrosine kinase 2* / PTK2 protein tyrosine kinase 2*  / complex / reaction






 

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