ENSGALG00000006840


Gallus gallus

Features
Gene ID: ENSGALG00000006840
  
Biological name :AKAP13
  
Synonyms : AKAP13 / A-kinase anchoring protein 13
  
Possible biological names infered from orthology : A-kinase anchor protein 13 / E9Q394 / Q12802
  
Species: Gallus gallus
  
Chr. number: 10
Strand: -1
Band:
Gene start: 13979803
Gene end: 14002167
  
Corresponding Affymetrix probe sets: Gga.8999.1.S1_at (Chicken Array)   GgaAffx.22069.1.S1_s_at (Chicken Array)   GgaAffx.22069.2.S1_at (Chicken Array)   GgaAffx.22069.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000011057
NCBI entrez gene - 415502     See in Manteia.
RefSeq - XM_015292059
RefSeq - XM_015292060
RefSeq - XM_015292061
swissprot - F1NIT0
Ensembl - ENSGALG00000006840
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AKAP13ENSDARG00000079994Danio rerio
 si:dkey-172h23.2ENSDARG00000023868Danio rerio
 AKAP13ENSG00000170776Homo sapiens
 Akap13ENSMUSG00000066406Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ARHGEF28 / Rho guanine nucleotide exchange factor 28 / Q8N1W1*ENSGALG0000001492334
Q6P9R4* / Q6ZSZ5* / ARHGEF18* / AC008878.3* / Rho guanine nucleotide exchange factor 18 * / Rho/Rac guanine nucleotide exchange factor 18*ENSGALG0000000357234
ARHGEF12 / Rho guanine nucleotide exchange factor 12 / Q8R4H2* / Q9NZN5* / Mus musculus Rho guanine nucleotide exchange factor (GEF) 12 (Arhgef12), transcript variant 2, mRNA.*ENSGALG0000000666318
ARHGEF11 / Rho guanine nucleotide exchange factor 11 / O15085* / Rho guanine nucleotide exchange factor (GEF) 11*ENSGALG0000003916314
ARHGEF3 / rho guanine nucleotide exchange factor 3 / Q91X46* / Q9NR81*ENSGALG000000054819
NET1 / neuroepithelial cell transforming 1 / Q7Z628* / Q9Z206* / neuroepithelial cell transforming gene 1*ENSGALG000000084378
ENSGALG000000264607


Protein motifs (from Interpro)
Interpro ID Name
 IPR000219  Dbl homology (DH) domain
 IPR001849  Pleckstrin homology domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0035023 regulation of Rho protein signal transduction IEA
 biological_processGO:0035025 positive regulation of Rho protein signal transduction IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0055007 cardiac muscle cell differentiation IEA
 biological_processGO:0060297 regulation of sarcomere organization IEA
 biological_processGO:0060348 bone development IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0071875 adrenergic receptor signaling pathway IEA
 biological_processGO:0086023 adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process IEA
 biological_processGO:1900169 regulation of glucocorticoid mediated signaling pathway IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005884 actin filament IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0030864 cortical actin cytoskeleton IEA
 molecular_functionGO:0004691 cAMP-dependent protein kinase activity IEA
 molecular_functionGO:0005078 MAP-kinase scaffold activity IEA
 molecular_functionGO:0005089 Rho guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA
 molecular_functionGO:0032947 protein-containing complex scaffold activity IEA
 molecular_functionGO:0051018 protein kinase A binding IEA


Pathways (from Reactome)
Pathway description
NRAGE signals death through JNK
Rho GTPase cycle
G alpha (12/13) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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