ENSGALG00000006051


Gallus gallus

Features
Gene ID: ENSGALG00000006051
  
Biological name :CDC7
  
Synonyms : CDC7 / cell division cycle 7
  
Possible biological names infered from orthology : Cell division cycle 7-related protein kinase / O00311 / Q9Z0H0
  
Species: Gallus gallus
  
Chr. number: 8
Strand: -1
Band:
Gene start: 14544898
Gene end: 14558894
  
Corresponding Affymetrix probe sets: GgaAffx.3765.1.S1_s_at (Chicken Array)   GgaAffx.3793.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000009735
NCBI entrez gene - 424507     See in Manteia.
RefSeq - XM_004936620
RefSeq - XM_422347
swissprot - F1NB13
Ensembl - ENSGALG00000006051
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cdc7ENSDARG00000023584Danio rerio
 CDC7ENSG00000097046Homo sapiens
 Cdc7ENSMUSG00000029283Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000727 double-strand break repair via break-induced replication IBA
 biological_processGO:0006270 DNA replication initiation IBA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006909 phagocytosis IBA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008360 regulation of cell shape IBA
 biological_processGO:0010571 positive regulation of nuclear cell cycle DNA replication IEA
 biological_processGO:0010971 positive regulation of G2/M transition of mitotic cell cycle IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0044770 cell cycle phase transition IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0045171 intercellular bridge IEA
 cellular_componentGO:0072686 mitotic spindle IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000000734 RPA2 / RPA4* / Q13156* / P15927* / replication protein A2* / replication protein A4*  / complex / reaction
 ENSGALG00000002663 ATR / ATR serine/threonine kinase / Q13535*  / reaction
 ENSGALG00000003072 RPA1 / Q5ZJJ2 / Replication protein A 70 kDa DNA-binding subunit / Q8VEE4* / P27694* / replication protein A1*  / complex / reaction
 ENSGALG00000010700 RPA3 / replication protein A3 / P35244* / Q9CQ71* / Replication protein A 14 kDa subunit *  / reaction / complex
 ENSGALG00000034198 MCM10 / minichromosome maintenance 10 replication initiation factor / Q0VBD2* / Q7L590*  / complex / reaction






 

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