ENSDARG00000023584


Danio rerio

Features
Gene ID: ENSDARG00000023584
  
Biological name :cdc7
  
Synonyms : cdc7 / cell division cycle 7 homolog (S. cerevisiae)
  
Possible biological names infered from orthology : cell division cycle 7 / Cell division cycle 7-related protein kinase / O00311 / Q9Z0H0
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 10863942
Gene end: 10877765
  
Corresponding Affymetrix probe sets: Dr.20362.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000032739
Ensembl peptide - ENSDARP00000118103
Ensembl peptide - ENSDARP00000091380
NCBI entrez gene - 492768     See in Manteia.
swissprot - B0UYI0
swissprot - B0UYH9
swissprot - B0UYH8
ZFIN ID - ZDB-GENE-041114-113
Ensembl - ENSDARG00000023584
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDC7ENSGALG00000006051Gallus gallus
 CDC7ENSG00000097046Homo sapiens
 Cdc7ENSMUSG00000029283Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000727 double-strand break repair via break-induced replication IBA
 biological_processGO:0006270 DNA replication initiation IBA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006909 phagocytosis IBA
 biological_processGO:0008360 regulation of cell shape IBA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000037188 rpa2 / replication protein A2 / RPA4* / Q13156* / P15927* / replication protein A4*  / reaction / complex
 ENSDARG00000074796 dbf4 / DBF4 zinc finger / A * / Q9QZ41* / Q9UBU7*  / complex
 ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit *  / complex / reaction
 ENSDARG00000026577 cdk2 / cyclin-dependent kinase 2 / P24941* / P97377*  / complex / reaction
 ENSDARG00000045815 mcm10 / Q5RHY1 / minichromosome maintenance 10 replication initiation factor / Q0VBD2* / Q7L590*  / reaction / complex
 ENSDARG00000043720 cdc45 / CDC45 cell division cycle 45 homolog (S. cerevisiae) / O75419* / Q9Z1X9* / cell division cycle 45* / Cell division control *  / complex / reaction






 

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