ENSDARG00000045815


Danio rerio

Features
Gene ID: ENSDARG00000045815
  
Biological name :mcm10
  
Synonyms : mcm10 / minichromosome maintenance 10 replication initiation factor / Q5RHY1
  
Possible biological names infered from orthology : Q0VBD2 / Q7L590
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 7851129
Gene end: 7869731
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000067338
NCBI entrez gene - 553396     See in Manteia.
RefSeq - NM_001024813
RefSeq Peptide - NP_001019984
swissprot - B7ZV42
swissprot - Q5RHY1
ZFIN ID - ZDB-GENE-041210-42
Ensembl - ENSDARG00000045815
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MCM10ENSGALG00000034198Gallus gallus
 MCM10ENSG00000065328Homo sapiens
 Mcm10ENSMUSG00000026669Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR015408  Zinc finger, Mcm10/DnaG-type
 IPR015411  Replication factor Mcm10, C-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006270 DNA replication initiation IBA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0031298 replication fork protection complex IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003688 DNA replication origin binding IBA
 molecular_functionGO:0003697 single-stranded DNA binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Activation of ATR in response to replication stress
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000026577 cdk2 / cyclin-dependent kinase 2 / P24941* / P97377*  / complex / reaction
 ENSDARG00000037188 rpa2 / replication protein A2 / RPA4* / Q13156* / P15927* / replication protein A4*  / reaction / complex
 ENSDARG00000074796 dbf4 / DBF4 zinc finger / A * / Q9QZ41* / Q9UBU7*  / complex / reaction
 ENSDARG00000023584 cdc7 / cell division cycle 7 homolog (S. cerevisiae) / Q9Z0H0* / O00311* / cell division cycle 7* / Cell division cycle 7-related protein kinase *  / reaction / complex
 ENSDARG00000003938 rpa1 / Q6NY74 / replication protein A1 / Q8VEE4* / P27694* / Replication protein A 70 kDa DNA-binding subunit *  / complex / reaction
 ENSDARG00000043720 cdc45 / CDC45 cell division cycle 45 homolog (S. cerevisiae) / O75419* / Q9Z1X9* / cell division cycle 45* / Cell division control *  / complex / reaction
 ENSDARG00000051854 cdt1 / chromatin licensing and DNA replication factor 1 / Q8R4E9* / Q9H211* / DNA replication factor Cdt1 *  / complex / reaction






 

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