ENSGALG00000006382


Gallus gallus

Features
Gene ID: ENSGALG00000006382
  
Biological name :PTPRJ
  
Synonyms : PTPRJ / receptor-type tyrosine-protein phosphatase eta precursor
  
Possible biological names infered from orthology : protein tyrosine phosphatase, receptor type J / Q12913
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 12815266
Gene end: 12882844
  
Corresponding Affymetrix probe sets: Gga.6654.1.A1_at (Chicken Array)   Gga.9159.1.S1_at (Chicken Array)   Gga.966.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010295
Ensembl peptide - ENSGALP00000042231
NCBI entrez gene - 395330     See in Manteia.
RefSeq - NM_204621
RefSeq Peptide - NP_989952
swissprot - F1P3J3
swissprot - R4GJB9
Ensembl - ENSGALG00000006382
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ptprjaENSDARG00000033042Danio rerio
 ptprjb.1ENSDARG00000091539Danio rerio
 ptprjb.2ENSDARG00000086511Danio rerio
 PTPRJENSG00000149177Homo sapiens
 PtprjENSMUSG00000025314Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTPRB / protein tyrosine phosphatase, receptor type B / B2RU80* / P23467*ENSGALG0000001004925
PTPRQ / protein tyrosine phosphatase, receptor type Q / P0C5E4* / Phosphatidylinositol phosphatase PTPRQ *ENSGALG0000001093523
PTPRO / receptor-type tyrosine-protein phosphatase O / E9Q612* / Q16827* / protein tyrosine phosphatase, receptor type O*ENSGALG0000001308518
PTPN9 / tyrosine-protein phosphatase non-receptor type 9 / O35239* / P43378* / protein tyrosine phosphatase, non-receptor type 9*ENSGALG0000000166411
ENSGALG0000000058410
ENSGALG000000213558
PTPN22 / protein tyrosine phosphatase, non-receptor type 22 / P29352* / Q9Y2R2* / Tyrosine-protein phosphatase non-receptor type 22 *ENSGALG000000216568
PTPN1 / tyrosine-protein phosphatase non-receptor type 1 / P18031* / P35821* / protein tyrosine phosphatase, non-receptor type 1*ENSGALG000000080108
PTPN2 / protein tyrosine phosphatase, non-receptor type 2 / P17706* / Q06180* / Tyrosine-protein phosphatase non-receptor type 2 *ENSGALG000000138677
P35831* / PTPN12* / Q05209* / protein tyrosine phosphatase, non-receptor type 12*ENSGALG000000425693


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0030155 regulation of cell adhesion IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0030336 negative regulation of cell migration IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0042059 negative regulation of epidermal growth factor receptor signaling pathway IEA
 biological_processGO:0043116 negative regulation of vascular permeability IEA
 biological_processGO:0043407 negative regulation of MAP kinase activity IEA
 biological_processGO:0045785 positive regulation of cell adhesion IEA
 biological_processGO:0048008 platelet-derived growth factor receptor signaling pathway IEA
 biological_processGO:0050860 negative regulation of T cell receptor signaling pathway IEA
 biological_processGO:0050918 positive chemotaxis IEA
 biological_processGO:0051894 positive regulation of focal adhesion assembly IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IEA
 biological_processGO:0051898 negative regulation of protein kinase B signaling IEA
 cellular_componentGO:0001772 immunological synapse IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0005161 platelet-derived growth factor receptor binding IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0045295 gamma-catenin binding IEA
 molecular_functionGO:0051019 mitogen-activated protein kinase binding IEA
 molecular_functionGO:0070097 delta-catenin binding IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Negative regulation of MET activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000033974 HGF / hepatocyte growth factor / P14210* / Q08048* / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain*  / reaction
 ENSGALG00000036883 MET / hepatocyte growth factor receptor precursor / P08581* / MET proto-oncogene, receptor tyrosine kinase*  / reaction






 

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