ENSDARG00000033042


Danio rerio

Features
Gene ID: ENSDARG00000033042
  
Biological name :ptprja
  
Synonyms : protein tyrosine phosphatase, receptor type, J a / ptprja
  
Possible biological names infered from orthology : protein tyrosine phosphatase, receptor type J / PTPRJ / Q12913
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 39553046
Gene end: 39611109
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000124678
NCBI entrez gene - 559679     See in Manteia.
swissprot - B6HY54
ZFIN ID - ZDB-GENE-030131-8301
Ensembl - ENSDARG00000033042
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTPRJENSGALG00000006382Gallus gallus
 PTPRJENSG00000149177Homo sapiens
 PtprjENSMUSG00000025314Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptprq / protein tyrosine phosphatase, receptor type, Q / P0C5E4* / Phosphatidylinositol phosphatase PTPRQ *ENSDARG0000000884919
ptprb / protein tyrosine phosphatase, receptor type, b / P23467*ENSDARG0000007662419
ptprjb.1 / protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 1 / PTPRJ* / Q12913* / protein tyrosine phosphatase, receptor type J*ENSDARG0000009153914
ptprh / protein tyrosine phosphatase, receptor type, hENSDARG0000007956014
ptprjb.2 / protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 2 / PTPRJ* / Q12913* / protein tyrosine phosphatase, receptor type J*ENSDARG0000008651113
ptprh / protein tyrosine phosphatase, receptor type, hENSDARG0000007829713
ptpro / protein tyrosine phosphatase, receptor type, O / E9Q612* / Q16827* / Receptor-type tyrosine-protein phosphatase O *ENSDARG000001104709
ptpn9b / protein tyrosine phosphatase, non-receptor type 9, bENSDARG000000739028
ptpn9a / protein tyrosine phosphatase, non-receptor type 9, a / PTPN9* / O35239* / P43378* / protein tyrosine phosphatase, non-receptor type 9*ENSDARG000000774958
ptpro / protein tyrosine phosphatase, receptor type, OENSDARG000001004227
ptpn2a / protein tyrosine phosphatase, non-receptor type 2, a / PTPN2* / P17706* / Q06180* / protein tyrosine phosphatase, non-receptor type 2* / Tyrosine-protein phosphatase non-receptor type 2 *ENSDARG000000164816
ptpn2b / protein tyrosine phosphatase, non-receptor type 2, b / PTPN2* / P17706* / Q06180* / protein tyrosine phosphatase, non-receptor type 2* / Tyrosine-protein phosphatase non-receptor type 2 *ENSDARG000000359866
ptpn22 / protein tyrosine phosphatase, non-receptor type 22 / P29352* / Q9Y2R2* / Tyrosine-protein phosphatase non-receptor type 22 *ENSDARG000001041976
ptpn18 / protein tyrosine phosphatase, non-receptor type 18 / Q61152* / Q99952*ENSDARG000000063086
ptpn1 / protein tyrosine phosphatase, non-receptor type 1 / P18031*ENSDARG000000079234


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 biological_processGO:0048844 artery morphogenesis IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Negative regulation of MET activity


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000007 blood blood decreased fluid flow , abnormal
Show

 ZFA:0000014 dorsal aorta dorsal aorta morphology , abnormal
dorsal aorta increased accumulation blood , abnormal
Show

 ZFA:0000477 posterior cardinal vein posterior cardinal vein increased accumulation blood , abnormal
Show

 ZFA:0001073 axial vasculature axial vasculature decreased functionality , abnormal
axial vasculature morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000045544 hgfa / hepatocyte growth factor a / HGF* / P14210* / Q08048* / hepatocyte growth factor* / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain*  / reaction
 ENSDARG00000070903 met / MET proto-oncogene, receptor tyrosine kinase / P08581*  / reaction






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr