ENSDARG00000016481


Danio rerio

Features
Gene ID: ENSDARG00000016481
  
Biological name :ptpn2a
  
Synonyms : protein tyrosine phosphatase, non-receptor type 2, a / ptpn2a
  
Possible biological names infered from orthology : P17706 / protein tyrosine phosphatase, non-receptor type 2 / PTPN2 / Q06180 / Tyrosine-protein phosphatase non-receptor type 2
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 10055492
Gene end: 10071887
  
Corresponding Affymetrix probe sets: Dr.10622.1.A1_at (Zebrafish Array)   NM_200466_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000118955
Ensembl peptide - ENSDARP00000109132
NCBI entrez gene - 393438     See in Manteia.
RefSeq - NM_200466
RefSeq Peptide - NP_956760
swissprot - F1QGX6
swissprot - F1Q8I4
ZFIN ID - ZDB-GENE-040426-1196
Ensembl - ENSDARG00000016481
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTPN2ENSGALG00000013867Gallus gallus
 PTPN2ENSG00000175354Homo sapiens
 Ptpn2ENSMUSG00000024539Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptpn2b / protein tyrosine phosphatase, non-receptor type 2, b / PTPN2* / P17706* / Q06180* / protein tyrosine phosphatase, non-receptor type 2* / Tyrosine-protein phosphatase non-receptor type 2 *ENSDARG0000003598663
ptpn1 / protein tyrosine phosphatase, non-receptor type 1 / P18031*ENSDARG0000000792342
ptpn9b / protein tyrosine phosphatase, non-receptor type 9, bENSDARG0000007390229
ptpn9a / protein tyrosine phosphatase, non-receptor type 9, a / PTPN9* / O35239* / P43378* / protein tyrosine phosphatase, non-receptor type 9*ENSDARG0000007749527
ptprja / protein tyrosine phosphatase, receptor type, J a / PTPRJ* / Q12913* / protein tyrosine phosphatase, receptor type J*ENSDARG0000003304226
ptprjb.1 / protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 1 / PTPRJ* / Q12913* / protein tyrosine phosphatase, receptor type J*ENSDARG0000009153926
ptpro / protein tyrosine phosphatase, receptor type, O / E9Q612* / Q16827* / Receptor-type tyrosine-protein phosphatase O *ENSDARG0000011047025
ptprh / protein tyrosine phosphatase, receptor type, hENSDARG0000007956025
ptprq / protein tyrosine phosphatase, receptor type, Q / P0C5E4* / Phosphatidylinositol phosphatase PTPRQ *ENSDARG0000000884925
ptprjb.2 / protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 2 / PTPRJ* / Q12913* / protein tyrosine phosphatase, receptor type J*ENSDARG0000008651125
ptpn22 / protein tyrosine phosphatase, non-receptor type 22 / P29352* / Q9Y2R2* / Tyrosine-protein phosphatase non-receptor type 22 *ENSDARG0000010419724
ptprb / protein tyrosine phosphatase, receptor type, b / P23467*ENSDARG0000007662424
ptprh / protein tyrosine phosphatase, receptor type, hENSDARG0000007829724
ptpn18 / protein tyrosine phosphatase, non-receptor type 18 / Q61152* / Q99952*ENSDARG0000000630823
ptpro / protein tyrosine phosphatase, receptor type, OENSDARG0000010042213


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR012265  Protein-tyrosine phosphatase, non-receptor type-1/2
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Negative regulation of MET activity
Regulation of IFNG signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000070903 met / MET proto-oncogene, receptor tyrosine kinase / P08581*  / reaction
 ENSDARG00000045544 hgfa / hepatocyte growth factor a / HGF* / P14210* / Q08048* / hepatocyte growth factor* / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain*  / reaction
 ENSDARG00000076182 stat1b / signal transducer and activator of transcription 1b / STAT1* / P42224* / signal transducer and activator of transcription 1*  / reaction






 

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