ENSDARG00000104197


Danio rerio

Features
Gene ID: ENSDARG00000104197
  
Biological name :ptpn22
  
Synonyms : protein tyrosine phosphatase, non-receptor type 22 / ptpn22
  
Possible biological names infered from orthology : P29352 / Q9Y2R2 / Tyrosine-protein phosphatase non-receptor type 22
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 26142613
Gene end: 26180539
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000131263
Ensembl peptide - ENSDARP00000141920
swissprot - A0A0R4IER5
swissprot - A0A0R4IWF7
ZFIN ID - ZDB-GENE-060503-458
Ensembl - ENSDARG00000104197
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTPN22ENSGALG00000021656Gallus gallus
 PTPN22ENSG00000134242Homo sapiens
 P29352ENSMUSG00000027843Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptpn18 / protein tyrosine phosphatase, non-receptor type 18 / Q61152* / Q99952*ENSDARG0000000630817
ptprq / protein tyrosine phosphatase, receptor type, Q / P0C5E4* / Phosphatidylinositol phosphatase PTPRQ *ENSDARG0000000884912
ptprjb.1 / protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 1 / PTPRJ* / Q12913* / protein tyrosine phosphatase, receptor type J*ENSDARG0000009153911
ptpn2a / protein tyrosine phosphatase, non-receptor type 2, a / PTPN2* / P17706* / Q06180* / protein tyrosine phosphatase, non-receptor type 2* / Tyrosine-protein phosphatase non-receptor type 2 *ENSDARG0000001648111
ptpn9a / protein tyrosine phosphatase, non-receptor type 9, a / PTPN9* / O35239* / P43378* / protein tyrosine phosphatase, non-receptor type 9*ENSDARG0000007749511
ptpn2b / protein tyrosine phosphatase, non-receptor type 2, b / PTPN2* / P17706* / Q06180* / protein tyrosine phosphatase, non-receptor type 2* / Tyrosine-protein phosphatase non-receptor type 2 *ENSDARG0000003598611
ptprh / protein tyrosine phosphatase, receptor type, hENSDARG0000007956011
ptprb / protein tyrosine phosphatase, receptor type, b / P23467*ENSDARG0000007662411
ptpn9b / protein tyrosine phosphatase, non-receptor type 9, bENSDARG0000007390211
ptpro / protein tyrosine phosphatase, receptor type, O / E9Q612* / Q16827* / Receptor-type tyrosine-protein phosphatase O *ENSDARG0000011047011
ptprjb.2 / protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 2 / PTPRJ* / Q12913* / protein tyrosine phosphatase, receptor type J*ENSDARG0000008651111
ptprja / protein tyrosine phosphatase, receptor type, J a / PTPRJ* / Q12913* / protein tyrosine phosphatase, receptor type J*ENSDARG0000003304211
ptprh / protein tyrosine phosphatase, receptor type, hENSDARG0000007829710
ptpn1 / protein tyrosine phosphatase, non-receptor type 1 / P18031*ENSDARG000000079239
ptpro / protein tyrosine phosphatase, receptor type, OENSDARG000001004226


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Phosphorylation of CD3 and TCR zeta chains


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000067996 csk / C-terminal Src kinase / P41240* / P41241* / Tyrosine-protein kinase CSK *  / complex






 

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