ENSDARG00000076624


Danio rerio

Features
Gene ID: ENSDARG00000076624
  
Biological name :ptprb
  
Synonyms : protein tyrosine phosphatase, receptor type, b / ptprb
  
Possible biological names infered from orthology : B2RU80 / P23467
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 74271067
Gene end: 74367912
  
Corresponding Affymetrix probe sets: Dr.12345.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000139766
Ensembl peptide - ENSDARP00000143178
NCBI entrez gene - 100149130     See in Manteia.
RefSeq - NM_001316727
RefSeq - XM_021474898
RefSeq - XM_021474899
RefSeq Peptide - NP_001303656
swissprot - A0A1L1QZQ6
swissprot - A0A0R4ITJ9
ZFIN ID - ZDB-GENE-101108-3
Ensembl - ENSDARG00000076624
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTPRBENSGALG00000010049Gallus gallus
 PTPRBENSG00000127329Homo sapiens
 PtprbENSMUSG00000020154Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ptprq / protein tyrosine phosphatase, receptor type, Q / P0C5E4* / Phosphatidylinositol phosphatase PTPRQ *ENSDARG0000000884919
ptprja / protein tyrosine phosphatase, receptor type, J a / PTPRJ* / Q12913* / protein tyrosine phosphatase, receptor type J*ENSDARG0000003304216
ptprh / protein tyrosine phosphatase, receptor type, hENSDARG0000007956011
ptprh / protein tyrosine phosphatase, receptor type, hENSDARG0000007829711
ptpro / protein tyrosine phosphatase, receptor type, O / E9Q612* / Q16827* / Receptor-type tyrosine-protein phosphatase O *ENSDARG000001104709
ptpn9a / protein tyrosine phosphatase, non-receptor type 9, a / PTPN9* / O35239* / P43378* / protein tyrosine phosphatase, non-receptor type 9*ENSDARG000000774958
ptpn9b / protein tyrosine phosphatase, non-receptor type 9, bENSDARG000000739028
ptprjb.1 / protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 1 / PTPRJ* / Q12913* / protein tyrosine phosphatase, receptor type J*ENSDARG000000915398
ptprjb.2 / protein tyrosine phosphatase, receptor type, Jb, tandem duplicate 2 / PTPRJ* / Q12913* / protein tyrosine phosphatase, receptor type J*ENSDARG000000865117
ptpro / protein tyrosine phosphatase, receptor type, OENSDARG000001004227
ptpn18 / protein tyrosine phosphatase, non-receptor type 18 / Q61152* / Q99952*ENSDARG000000063085
ptpn22 / protein tyrosine phosphatase, non-receptor type 22 / P29352* / Q9Y2R2* / Tyrosine-protein phosphatase non-receptor type 22 *ENSDARG000001041975
ptpn2a / protein tyrosine phosphatase, non-receptor type 2, a / PTPN2* / P17706* / Q06180* / protein tyrosine phosphatase, non-receptor type 2* / Tyrosine-protein phosphatase non-receptor type 2 *ENSDARG000000164815
ptpn2b / protein tyrosine phosphatase, non-receptor type 2, b / PTPN2* / P17706* / Q06180* / protein tyrosine phosphatase, non-receptor type 2* / Tyrosine-protein phosphatase non-receptor type 2 *ENSDARG000000359865
ptpn1 / protein tyrosine phosphatase, non-receptor type 1 / P18031*ENSDARG000000079234


Protein motifs (from Interpro)
Interpro ID Name
 IPR000242  PTP type protein phosphatase
 IPR000387  Tyrosine specific protein phosphatases domain
 IPR003595  Protein-tyrosine phosphatase, catalytic
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR016130  Protein-tyrosine phosphatase, active site
 IPR029021  Protein-tyrosine phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development IMP
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0035335 peptidyl-tyrosine dephosphorylation IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004725 protein tyrosine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000180 caudal vein caudal vein increased permeability , abnormal
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 ZFA:0001114 head head hemorrhagic , abnormal
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 ZFA:0001286 caudal vein plexus caudal vein plexus disorganized , abnormal
caudal vein plexus broken , abnormal
caudal vein plexus increased accumulation blood , abnormal
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 ZFA:0005025 dorsal longitudinal anastomotic vessel dorsal longitudinal anastomotic vessel increased permeability , abnormal
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 ZFA:0009036 blood vessel endothelial cell blood vessel endothelial cell has fewer parts of type blood vessel endothelial cell cell-cell junction, abnormal
blood vessel endothelial cell adherens junction immature , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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