ENSGALG00000006552


Gallus gallus

Features
Gene ID: ENSGALG00000006552
  
Biological name :INS-IGF2
  
Synonyms : INS-IGF2 / Insulin Insulin B chain Insulin A chain / P67970
  
Possible biological names infered from orthology : F8WCM5 / INS / Ins1 / Ins2 / INS-IGF2 readthrough / insulin / Insulin-1 Insulin-1 B chain Insulin-1 A chain / Insulin-2 Insulin-2 B chain Insulin-2 A chain / P01308 / P01325 / P01326
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 13745653
Gene end: 13750317
  
Corresponding Affymetrix probe sets: Gga.673.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010567
NCBI entrez gene - 396145     See in Manteia.
RefSeq - NM_205222
RefSeq - XM_015286579
RefSeq Peptide - NP_990553
swissprot - P67970
Ensembl - ENSGALG00000006552
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 insENSDARG00000035350Danio rerio
 insbENSDARG00000034610Danio rerio
 F8WCM5ENSG00000129965Homo sapiens
 INSENSG00000254647Homo sapiens
 Ins1ENSMUSG00000035804Mus musculus
 Ins2ENSMUSG00000000215Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004825  Insulin
 IPR016179  Insulin-like
 IPR022352  Insulin family
 IPR022353  Insulin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003407 neural retina development TAS
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006006 glucose metabolic process IEA
 biological_processGO:0008283 cell proliferation IDA
 biological_processGO:0010467 gene expression IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0043066 negative regulation of apoptotic process IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IDA
 molecular_functionGO:0005179 hormone activity IEA


Pathways (from Reactome)
Pathway description
Insulin processing
Synthesis, secretion, and deacylation of Ghrelin
COPI-mediated anterograde transport
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
IRS activation
Signal attenuation
Insulin receptor signalling cascade
Signaling by Insulin receptor
Insulin receptor recycling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000013100 GRB10 / growth factor receptor bound protein 10 / Q13322* / Q60760*  / reaction / complex
 ENSGALG00000039775 SHC1 / SHC adaptor protein 1 / P29353* / P98083* / SHC-transforming protein 1 *  / complex / reaction
 ENSGALG00000006552 P67970 / INS-IGF2 / Insulin Insulin B chain Insulin A chain / INS* / Ins1* / Ins2* / F8WCM5* / P01308* / P01325* / P01326* / insulin* / INS-IGF2 readthrough* / Insulin-1 Insulin-1 B chain I...  / reaction / complex
 ENSGALG00000040758 INSR / insulin receptor / P06213* / P15208* / Insulin receptor Insulin receptor subunit alpha Insulin receptor subunit beta*  / reaction / complex






 

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