ENSGALG00000006702


Gallus gallus

Features
Gene ID: ENSGALG00000006702
  
Biological name :MFGE8
  
Synonyms : lactadherin isoform 2 precursor / MFGE8
  
Possible biological names infered from orthology : milk fat globule-EGF factor 8 protein / P21956 / Q08431
  
Species: Gallus gallus
  
Chr. number: 10
Strand: 1
Band:
Gene start: 13033323
Gene end: 13040620
  
Corresponding Affymetrix probe sets: Gga.16498.1.S1_at (Chicken Array)   Gga.7807.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000010820
NCBI entrez gene - 415494     See in Manteia.
RefSeq - NM_001277110
RefSeq - NM_001277111
RefSeq Peptide - NP_001264040
RefSeq Peptide - NP_001264039
swissprot - E1C0K5
Ensembl - ENSGALG00000006702
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MFGE8ENSG00000140545Homo sapiens
 Mfge8ENSMUSG00000030605Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EDIL3 / EGF like repeats and discoidin domains 3 / O35474* / O43854* / EGF-like repeat and discoidin I-like domain-containing protein 3 *ENSGALG0000001563054
F8 / coagulation factor VIII / P00451* / Q06194*ENSGALG0000000507737
F5 / coagulation factor V / O88783* / P12259* / Coagulation factor V Coagulation factor V heavy chain Coagulation factor V light chain*ENSGALG0000002929835
NRP2 / neuropilin-2 precursor / O35375* / O60462* / neuropilin 2*ENSGALG0000000862128
NRP1 / neuropilin-1 precursor / O14786* / P97333* / neuropilin 1*ENSGALG0000000714027
DCBLD2 / discoidin, CUB and LCCL domain-containing protein 2 precursor / Q91ZV3* / Q96PD2* / discoidin, CUB and LCCL domain containing 2* / Mus musculus discoidin, CUB and LCCL domain cont...ENSGALG0000001525821
DCBLD1 / discoidin, CUB and LCCL domain containing 1 / Q8N8Z6* / Q9D4J3* / Mus musculus discoidin, CUB and LCCL domain containing 1 (Dcbld1), transcript variant 2, mRNA.*ENSGALG0000001490719
ENSGALG0000002906616
RS1 / retinoschisin 1 / O15537* / Q9Z1L4* / retinoschisis (X-linked, juvenile) 1 (human)*ENSGALG0000001652314
HEPH / hephaestin / Q9BQS7* / Q9Z0Z4*ENSGALG0000003741011
ENSGALG0000003077310
HEPHL1 / hephaestin like 1 / Q3V1H3* / Q6MZM0* / Hephaestin-like protein 1 *ENSGALG000000430279


Protein motifs (from Interpro)
Interpro ID Name
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000421  Coagulation factor 5/8 C-terminal domain
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR027060  Lactadherin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006910 phagocytosis, recognition IEA
 biological_processGO:0006911 phagocytosis, engulfment IEA
 biological_processGO:0043277 apoptotic cell clearance IEA
 biological_processGO:0050766 positive regulation of phagocytosis IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0019897 extrinsic component of plasma membrane IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0001786 phosphatidylserine binding IEA
 molecular_functionGO:0005178 integrin binding IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0008429 phosphatidylethanolamine binding IEA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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