ENSGALG00000008621


Gallus gallus

Features
Gene ID: ENSGALG00000008621
  
Biological name :NRP2
  
Synonyms : neuropilin-2 precursor / NRP2
  
Possible biological names infered from orthology : neuropilin 2 / O35375 / O60462
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 12719089
Gene end: 12797247
  
Corresponding Affymetrix probe sets: Gga.2538.2.S1_a_at (Chicken Array)   Gga.2538.3.S1_a_at (Chicken Array)   GgaAffx.21106.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000014032
Ensembl peptide - ENSGALP00000054748
Ensembl peptide - ENSGALP00000045108
Ensembl peptide - ENSGALP00000044853
NCBI entrez gene - 374157     See in Manteia.
RefSeq - XM_015289367
RefSeq - XM_015289370
RefSeq - XM_015289369
RefSeq - XM_015289368
RefSeq - NM_204284
RefSeq Peptide - NP_989615
swissprot - E1BZ39
swissprot - A0A1D5NWW0
swissprot - A0A1D5NXL0
swissprot - A0A1D5PPE9
Ensembl - ENSGALG00000008621
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NRP2ENSG00000118257Homo sapiens
 Nrp2ENSMUSG00000025969Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NRP1 / neuropilin-1 precursor / O14786* / P97333* / neuropilin 1*ENSGALG0000000714042
F8 / coagulation factor VIII / P00451* / Q06194*ENSGALG0000000507718
F5 / coagulation factor V / O88783* / P12259* / Coagulation factor V Coagulation factor V heavy chain Coagulation factor V light chain*ENSGALG0000002929816
MFGE8 / lactadherin isoform 2 precursor / P21956* / Q08431* / milk fat globule-EGF factor 8 protein*ENSGALG0000000670214
EDIL3 / EGF like repeats and discoidin domains 3 / O35474* / O43854* / EGF-like repeat and discoidin I-like domain-containing protein 3 *ENSGALG0000001563013
DCBLD1 / discoidin, CUB and LCCL domain containing 1 / Q8N8Z6* / Q9D4J3* / Mus musculus discoidin, CUB and LCCL domain containing 1 (Dcbld1), transcript variant 2, mRNA.*ENSGALG0000001490712
DCBLD2 / discoidin, CUB and LCCL domain-containing protein 2 precursor / Q91ZV3* / Q96PD2* / discoidin, CUB and LCCL domain containing 2* / Mus musculus discoidin, CUB and LCCL domain cont...ENSGALG0000001525811
ENSGALG0000002906610
HEPHL1 / hephaestin like 1 / Q3V1H3* / Q6MZM0* / Hephaestin-like protein 1 *ENSGALG000000430278
HEPH / hephaestin / Q9BQS7* / Q9Z0Z4*ENSGALG000000374107
ENSGALG000000307737
RS1 / retinoschisin 1 / O15537* / Q9Z1L4* / retinoschisis (X-linked, juvenile) 1 (human)*ENSGALG000000165235


Protein motifs (from Interpro)
Interpro ID Name
 IPR000421  Coagulation factor 5/8 C-terminal domain
 IPR000859  CUB domain
 IPR000998  MAM domain
 IPR008979  Galactose-binding-like domain superfamily
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR014648  Neuropilin
 IPR022579  Neuropilin, C-terminal
 IPR027143  Neuropilin-2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001755 neural crest cell migration IEA
 biological_processGO:0001764 neuron migration IEA
 biological_processGO:0003148 outflow tract septum morphogenesis IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007411 axon guidance IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0021612 facial nerve structural organization IEA
 biological_processGO:0021649 vestibulocochlear nerve structural organization IEA
 biological_processGO:0021675 nerve development IEA
 biological_processGO:0021828 gonadotrophin-releasing hormone neuronal migration to the hypothalamus IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0036486 ventral trunk neural crest cell migration IEA
 biological_processGO:0038084 vascular endothelial growth factor signaling pathway IEA
 biological_processGO:0048846 axon extension involved in axon guidance IEA
 biological_processGO:0050919 negative chemotaxis IEA
 biological_processGO:0061549 sympathetic ganglion development IEA
 biological_processGO:0061551 trigeminal ganglion development IEA
 biological_processGO:0071526 semaphorin-plexin signaling pathway IEA
 biological_processGO:0097374 sensory neuron axon guidance IEA
 biological_processGO:0097490 sympathetic neuron projection extension IEA
 biological_processGO:0097491 sympathetic neuron projection guidance IEA
 biological_processGO:1901166 neural crest cell migration involved in autonomic nervous system development IEA
 biological_processGO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance IEA
 biological_processGO:1903375 facioacoustic ganglion development IEA
 biological_processGO:1904835 dorsal root ganglion morphogenesis IEA
 biological_processGO:1990830 cellular response to leukemia inhibitory factor IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon IEA
 molecular_functionGO:0005021 vascular endothelial growth factor-activated receptor activity IEA
 molecular_functionGO:0017154 semaphorin receptor activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Neurophilin interactions with VEGF and VEGFR


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008621 NRP2 / neuropilin-2 precursor / O35375* / O60462* / neuropilin 2*  / reaction / complex






 

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