ENSGALG00000006824


Gallus gallus

Features
Gene ID: ENSGALG00000006824
  
Biological name :USP19
  
Synonyms : ubiquitin specific peptidase 19 / USP19
  
Possible biological names infered from orthology : O94966 / Q3UJD6
  
Species: Gallus gallus
  
Chr. number: 12
Strand: 1
Band:
Gene start: 11595017
Gene end: 11615187
  
Corresponding Affymetrix probe sets: GgaAffx.4243.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044856
Ensembl peptide - ENSGALP00000053018
Ensembl peptide - ENSGALP00000052320
Ensembl peptide - ENSGALP00000011018
NCBI entrez gene - 100858727     See in Manteia.
RefSeq - XM_015293328
RefSeq - XM_015293324
RefSeq - XM_015293325
RefSeq - XM_015293326
RefSeq - XM_015293327
RefSeq - XM_003642004
RefSeq - XM_004944628
RefSeq - XM_004944629
RefSeq - XM_004944630
swissprot - A0A1D5PJM2
swissprot - A0A1D5PHP0
swissprot - F1NES4
swissprot - A0A1D5NWW3
Ensembl - ENSGALG00000006824
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 usp19ENSDARG00000004132Danio rerio
 USP19ENSG00000172046Homo sapiens
 Usp19ENSMUSG00000006676Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
USP6* / USP32* / P35125* / Q8NFA0* / ubiquitin specific peptidase 6* / ubiquitin specific peptidase 32*ENSGALG0000000535019
USP15 / ubiquitin carboxyl-terminal hydrolase 15 isoform 1 / Q8R5H1* / Q9Y4E8* / ubiquitin specific peptidase 15*ENSGALG0000003002419
USP4 / ubiquitin carboxyl-terminal hydrolase 4 / Q13107* / P35123* / ubiquitin specific peptidase 4* / ubiquitin specific peptidase 4 (proto-oncogene)*ENSGALG0000000379918
USP31 / ubiquitin specific peptidase 31 / Q70CQ4*ENSGALG0000000628615
USP43* / Q70EL4* / Q8BUM9* / ubiquitin specific peptidase 43*ENSGALG000000378126


Protein motifs (from Interpro)
Interpro ID Name
 IPR001394  Peptidase C19, ubiquitin carboxyl-terminal hydrolase
 IPR002893  Zinc finger, MYND-type
 IPR007052  CS domain
 IPR008978  HSP20-like chaperone
 IPR018200  Ubiquitin specific protease, conserved site
 IPR028889  Ubiquitin specific protease domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016579 protein deubiquitination IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IEA
 biological_processGO:0034976 response to endoplasmic reticulum stress IEA
 biological_processGO:0048642 negative regulation of skeletal muscle tissue development IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0071108 protein K48-linked deubiquitination IEA
 biological_processGO:1900037 regulation of cellular response to hypoxia IEA
 biological_processGO:1901799 negative regulation of proteasomal protein catabolic process IEA
 biological_processGO:1904292 regulation of ERAD pathway IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004843 thiol-dependent ubiquitin-specific protease activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0036459 thiol-dependent ubiquitinyl hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051879 Hsp90 protein binding IEA
 molecular_functionGO:1990380 Lys48-specific deubiquitinase activity IEA


Pathways (from Reactome)
Pathway description
Ub-specific processing proteases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002486 RNF123 / ring finger protein 123 / Q5XPI3* / Q5XPI4*  / complex
 ENSGALG00000017186 BIRC2 / BIRC3* / Q62210* / Q13489* / Q13490* / baculoviral IAP repeat containing 2* / baculoviral IAP repeat containing 3* / Baculoviral IAP repeat-containing protein 2 *  / reaction / complex






 

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