ENSGALG00000007109


Gallus gallus

Features
Gene ID: ENSGALG00000007109
  
Biological name :APOA4
  
Synonyms : APOA4 / apolipoprotein A4
  
Possible biological names infered from orthology : Apolipoprotein A-IV / P06727 / P06728
  
Species: Gallus gallus
  
Chr. number: 24
Strand: -1
Band:
Gene start: 5107031
Gene end: 5108520
  
Corresponding Affymetrix probe sets: Gga.462.1.S1_x_at (Chicken Array)   Gga.462.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000011502
NCBI entrez gene - 395780     See in Manteia.
RefSeq - NM_204938
RefSeq Peptide - NP_990269
swissprot - O93601
Ensembl - ENSGALG00000007109
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 apoa4aENSDARG00000101160Danio rerio
 apoa4b.1ENSDARG00000040298Danio rerio
 apoa4b.2ENSDARG00000094929Danio rerio
 apoa4b.2ENSDARG00000020866Danio rerio
 APOA4ENSG00000110244Homo sapiens
 Apoa4ENSMUSG00000032080Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
APOA5 / apolipoprotein A5 / Q6Q788* / Q8C7G5* / Mus musculus apolipoprotein A-V (Apoa5), transcript variant 2, mRNA.*ENSGALG0000001436820
APOA1 / P08250 / Apolipoprotein A-I Proapolipoprotein A-I / P02647* / Q00623* / apolipoprotein A1* / Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I*ENSGALG0000000711414


Protein motifs (from Interpro)
Interpro ID Name
 IPR000074  Apolipoprotein A/E


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002227 innate immune response in mucosa IEA
 biological_processGO:0006695 cholesterol biosynthetic process IBA
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0006982 response to lipid hydroperoxide IEA
 biological_processGO:0007159 leukocyte cell-cell adhesion IEA
 biological_processGO:0008203 cholesterol metabolic process IEA
 biological_processGO:0010873 positive regulation of cholesterol esterification IEA
 biological_processGO:0010898 positive regulation of triglyceride catabolic process IEA
 biological_processGO:0019430 removal of superoxide radicals IEA
 biological_processGO:0019433 triglyceride catabolic process IBA
 biological_processGO:0030300 regulation of intestinal cholesterol absorption IEA
 biological_processGO:0031102 neuron projection regeneration IBA
 biological_processGO:0032374 regulation of cholesterol transport IEA
 biological_processGO:0033344 cholesterol efflux IEA
 biological_processGO:0033700 phospholipid efflux IEA
 biological_processGO:0034372 very-low-density lipoprotein particle remodeling IEA
 biological_processGO:0034380 high-density lipoprotein particle assembly IBA
 biological_processGO:0034445 negative regulation of plasma lipoprotein oxidation IEA
 biological_processGO:0035634 response to stilbenoid IEA
 biological_processGO:0042157 lipoprotein metabolic process IBA
 biological_processGO:0042632 cholesterol homeostasis IEA
 biological_processGO:0042744 hydrogen peroxide catabolic process IEA
 biological_processGO:0043691 reverse cholesterol transport IEA
 biological_processGO:0045723 positive regulation of fatty acid biosynthetic process IEA
 biological_processGO:0046470 phosphatidylcholine metabolic process IEA
 biological_processGO:0051006 positive regulation of lipoprotein lipase activity IEA
 biological_processGO:0055088 lipid homeostasis IEA
 biological_processGO:0065005 protein-lipid complex assembly IEA
 biological_processGO:0070328 triglyceride homeostasis IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 cellular_componentGO:0034361 very-low-density lipoprotein particle IEA
 cellular_componentGO:0034364 high-density lipoprotein particle IEA
 cellular_componentGO:0042627 chylomicron IEA
 cellular_componentGO:0072562 blood microparticle IBA
 molecular_functionGO:0005507 copper ion binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015485 cholesterol binding IBA
 molecular_functionGO:0016209 antioxidant activity IEA
 molecular_functionGO:0017127 cholesterol transporter activity IEA
 molecular_functionGO:0031210 phosphatidylcholine binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity IEA


Pathways (from Reactome)
Pathway description
Chylomicron assembly
Retinoid metabolism and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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