ENSDARG00000040298


Danio rerio

Features
Gene ID: ENSDARG00000040298
  
Biological name :apoa4b.1
  
Synonyms : apoa4b.1 / apolipoprotein A-IV b, tandem duplicate 1
  
Possible biological names infered from orthology : APOA4 / APOA5 / apolipoprotein A4 / apolipoprotein A5 / Apolipoprotein A-IV / Mus musculus apolipoprotein A-V (Apoa5), transcript variant 2, mRNA. / P06727 / P06728 / Q6Q788 / Q8C7G5
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 23913943
Gene end: 23916263
  
Corresponding Affymetrix probe sets: Dr.5488.1.S1_at (Zebrafish Array)   Dr.5488.2.A1_a_at (Zebrafish Array)   NM_001079861_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000111399
Ensembl peptide - ENSDARP00000144621
NCBI entrez gene - 322543     See in Manteia.
RefSeq - NM_001079861
RefSeq Peptide - NP_001073330
swissprot - F1QHR0
ZFIN ID - ZDB-GENE-030131-1263
Ensembl - ENSDARG00000040298
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 APOA4ENSGALG00000007109Gallus gallus
 APOA5ENSGALG00000014368Gallus gallus
 APOA4ENSG00000110244Homo sapiens
 APOA5ENSG00000110243Homo sapiens
 Apoa4ENSMUSG00000032080Mus musculus
 Apoa5ENSMUSG00000032079Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
apoa4b.2 / apolipoprotein A-IV b, tandem duplicate 2 / APOA4* / APOA5* / Q8C7G5* / P06727* / P06728* / Q6Q788* / apolipoprotein A5* / apolipoprotein A4* / Apolipoprotein A-IV * / Mus muscul...ENSDARG0000002086690
apoa4b.3 / apoa4b.2 / apolipoprotein A-IV b, tandem duplicate 3 / APOA4* / APOA5* / Q8C7G5* / P06727* / P06728* / Q6Q788* / apolipoprotein A5* / apolipoprotein A4* / Apolipoprotein A-IV * /...ENSDARG0000009492989
apoa4a / apolipoprotein A-IV a / APOA4* / APOA5* / Q8C7G5* / P06727* / P06728* / Q6Q788* / apolipoprotein A5* / apolipoprotein A4* / Apolipoprotein A-IV * / Mus musculus apolipoprotein A-V ...ENSDARG0000010116043
apoa1a / O42363 / apolipoprotein A-Ia / APOA1* / Q00623* / P02647* / apolipoprotein A1* / Apolipoprotein A-I Proapolipoprotein A-I Truncated apolipoprotein A-I*ENSDARG0000001207622
apoa1b / apolipoprotein A-Ib / APOA1* / P02647* / apolipoprotein A1*ENSDARG0000010132418


Protein motifs (from Interpro)
Interpro ID Name
 IPR000074  Apolipoprotein A/E


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006695 cholesterol biosynthetic process IBA
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0010873 positive regulation of cholesterol esterification IBA
 biological_processGO:0010898 positive regulation of triglyceride catabolic process IBA
 biological_processGO:0019433 triglyceride catabolic process IBA
 biological_processGO:0030300 regulation of intestinal cholesterol absorption IBA
 biological_processGO:0031102 neuron projection regeneration IBA
 biological_processGO:0033344 cholesterol efflux IBA
 biological_processGO:0033700 phospholipid efflux IBA
 biological_processGO:0034372 very-low-density lipoprotein particle remodeling IBA
 biological_processGO:0034380 high-density lipoprotein particle assembly IBA
 biological_processGO:0042157 lipoprotein metabolic process IBA
 biological_processGO:0042632 cholesterol homeostasis IBA
 biological_processGO:0043691 reverse cholesterol transport IBA
 biological_processGO:0045723 positive regulation of fatty acid biosynthetic process IBA
 biological_processGO:0046470 phosphatidylcholine metabolic process IBA
 biological_processGO:0051006 positive regulation of lipoprotein lipase activity IBA
 biological_processGO:0070328 triglyceride homeostasis IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0034364 high-density lipoprotein particle IBA
 cellular_componentGO:0042627 chylomicron IBA
 cellular_componentGO:0072562 blood microparticle IBA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0015485 cholesterol binding IBA
 molecular_functionGO:0017127 cholesterol transporter activity IBA
 molecular_functionGO:0031210 phosphatidylcholine binding IBA
 molecular_functionGO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity IBA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Chylomicron assembly
Retinoid metabolism and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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