ENSGALG00000008837


Gallus gallus

Features
Gene ID: ENSGALG00000008837
  
Biological name :PELI1
  
Synonyms : E3 ubiquitin-protein ligase pellino homolog 1 / PELI1
  
Possible biological names infered from orthology : pellino 1 / pellino E3 ubiquitin protein ligase 1 / Q8C669 / Q96FA3
  
Species: Gallus gallus
  
Chr. number: 3
Strand: -1
Band:
Gene start: 9637569
Gene end: 9655444
  
Corresponding Affymetrix probe sets: GgaAffx.12100.1.S1_s_at (Chicken Array)   GgaAffx.12100.2.A1_at (Chicken Array)   GgaAffx.12100.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000038747
NCBI entrez gene - 421279     See in Manteia.
RefSeq - XM_015278051
RefSeq - NM_001012872
RefSeq - XM_015278049
RefSeq - XM_015278050
RefSeq - XM_015278047
RefSeq - XM_015278048
RefSeq Peptide - NP_001012890
swissprot - F6UK83
Ensembl - ENSGALG00000008837
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PELI1ENSG00000197329Homo sapiens
 Peli1ENSMUSG00000020134Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PELI2 / pellino E3 ubiquitin protein ligase family member 2 / Q9HAT8*ENSGALG0000001212482


Protein motifs (from Interpro)
Interpro ID Name
 IPR006800  Pellino family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0001819 positive regulation of cytokine production IEA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0008063 Toll signaling pathway IBA
 biological_processGO:0030890 positive regulation of B cell proliferation IEA
 biological_processGO:0031398 positive regulation of protein ubiquitination IEA
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0034141 positive regulation of toll-like receptor 3 signaling pathway IEA
 biological_processGO:0034145 positive regulation of toll-like receptor 4 signaling pathway IEA
 biological_processGO:0042130 negative regulation of T cell proliferation IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0043331 response to dsRNA IEA
 biological_processGO:0050868 negative regulation of T cell activation IEA
 biological_processGO:0050871 positive regulation of B cell activation IEA
 biological_processGO:0070936 protein K48-linked ubiquitination IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
Interleukin-1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008015 UBE2V1 / ubiquitin-conjugating enzyme E2 variant 1 / Q13404* / ubiquitin conjugating enzyme E2 V1*  / complex
 ENSGALG00000012124 PELI2 / pellino E3 ubiquitin protein ligase family member 2 / Q9HAT8*  / reaction
 ENSGALG00000037716 UBA52 / ubiquitin A-52 residue ribosomal protein fusion product 1 / P62984* / P62987* / Gm5239* / Gm11808* / predicted gene 11808*  / complex
 ENSGALG00000009586 IRAK4 / interleukin-1 receptor-associated kinase 4 / Q8R4K2* / Q9NWZ3*  / complex / reaction
 ENSGALG00000008837 PELI1 / E3 ubiquitin-protein ligase pellino homolog 1 / Q8C669* / Q96FA3* / pellino 1* / pellino E3 ubiquitin protein ligase 1*  / reaction
 ENSGALG00000036790 P79781 / RPS27A / Ubiquitin-40S ribosomal protein S27a Ubiquitin 40S ribosomal protein S27a / P62983* / P62979* / AL136454.1* / ribosomal protein S27a*  / complex






 

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