ENSGALG00000008873


Gallus gallus

Features
Gene ID: ENSGALG00000008873
  
Biological name :POLE3
  
Synonyms : DNA polymerase epsilon 3, accessory subunit / POLE3
  
Possible biological names infered from orthology : polymerase (DNA directed), epsilon 3 (p17 subunit) / Q9NRF9
  
Species: Gallus gallus
  
Chr. number: 17
Strand: 1
Band:
Gene start: 1934343
Gene end: 1938562
  
Corresponding Affymetrix probe sets: Gga.5487.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000039553
NCBI entrez gene - 417275     See in Manteia.
RefSeq - NM_001025354
RefSeq Peptide - NP_001020525
swissprot - F1P2L0
Ensembl - ENSGALG00000008873
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pole3ENSDARG00000008551Danio rerio
 POLE3ENSG00000148229Homo sapiens
 Pole3ENSMUSG00000028394Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NFYB / P25207 / Nuclear transcription factor Y subunit beta / P25208* / P63139*ENSGALG0000004119328


Protein motifs (from Interpro)
Interpro ID Name
 IPR003958  Transcription factor CBF/NF-Y/archaeal histone domain
 IPR009072  Histone-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043966 histone H3 acetylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005671 Ada2/Gcn5/Ada3 transcription activator complex IEA
 cellular_componentGO:0008622 epsilon DNA polymerase complex IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Recognition of DNA damage by PCNA-containing replication complex
Telomere C-strand synthesis initiation
PCNA-Dependent Long Patch Base Excision Repair
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Dual Incision in GG-NER
Dual incision in TC-NER
DNA replication initiation
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000016312 POLA1 / DNA polymerase alpha 1, catalytic subunit / P09884* / P33609* / polymerase (DNA directed), alpha 1*  / complex / reaction
 ENSGALG00000016278 PRIM2 / DNA primase subunit 2 / P33610* / P49643* / DNA primase large subunit *  / reaction / complex
 ENSGALG00000012237 POLE2 / Q5ZKQ6 / DNA polymerase epsilon subunit 2 / O54956* / P56282* / AC099934.2* / DNA polymerase epsilon 2, accessory subunit* / polymerase (DNA directed), epsilon 2 (p59 subunit)*  / complex






 

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contact: otassy@igbmc.fr