ENSDARG00000008551


Danio rerio

Features
Gene ID: ENSDARG00000008551
  
Biological name :pole3
  
Synonyms : pole3 / polymerase (DNA directed), epsilon 3 (p17 subunit)
  
Possible biological names infered from orthology : DNA polymerase epsilon 3, accessory subunit / Q9NRF9
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 32888119
Gene end: 32890807
  
Corresponding Affymetrix probe sets: Dr.14292.1.S1_at (Zebrafish Array)   NM_200801_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000002886
NCBI entrez gene - 393774     See in Manteia.
RefSeq - NM_200801
RefSeq Peptide - NP_957095
swissprot - Q6PBL4
ZFIN ID - ZDB-GENE-040426-1773
Ensembl - ENSDARG00000008551
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 POLE3ENSGALG00000008873Gallus gallus
 POLE3ENSG00000148229Homo sapiens
 Pole3ENSMUSG00000028394Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nfyba / nuclear transcription factor Y, beta a / NFYB* / P25208* / P63139* / nuclear transcription factor Y subunit beta*ENSDARG0000003918526
nfybb / nuclear transcription factor Y, beta b / NFYB* / P25208* / P63139* / nuclear transcription factor Y subunit beta*ENSDARG0000004561126


Protein motifs (from Interpro)
Interpro ID Name
 IPR003958  Transcription factor CBF/NF-Y/archaeal histone domain
 IPR009072  Histone-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Recognition of DNA damage by PCNA-containing replication complex
Telomere C-strand synthesis initiation
PCNA-Dependent Long Patch Base Excision Repair
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
DNA replication initiation
Activation of the pre-replicative complex


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000052721 prim2 / DNA primase subunit 2 / P33610* / P49643* / DNA primase large subunit *  / reaction / complex
 ENSDARG00000013016 pole4 / polymerase (DNA-directed), epsilon 4, accessory subunit / Q9CQ36* / Q9NR33* / DNA polymerase epsilon 4, accessory subunit* / polymerase (DNA-directed), epsilon 4 (p12 subunit)*  / complex
 ENSDARG00000015070 pola2 / polymerase (DNA directed), alpha 2 / P33611* / Q14181* / DNA polymerase alpha 2, accessory subunit*  / complex / reaction
 ENSDARG00000058533 pole / polymerase (DNA directed), epsilon / Q07864* / Q9WVF7* / DNA polymerase epsilon, catalytic subunit*  / complex
 ENSDARG00000045308 pola1 / polymerase (DNA directed), alpha 1 / P09884* / P33609* / DNA polymerase alpha 1, catalytic subunit*  / reaction / complex






 

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