ENSGALG00000008985


Gallus gallus

Features
Gene ID: ENSGALG00000008985
  
Biological name :SRI
  
Synonyms : sorcin / SRI
  
Possible biological names infered from orthology : P30626 / Q6P069
  
Species: Gallus gallus
  
Chr. number: 2
Strand: -1
Band:
Gene start: 21011047
Gene end: 21019985
  
Corresponding Affymetrix probe sets: Gga.1185.2.S1_s_at (Chicken Array)   GgaAffx.11659.1.S1_at (Chicken Array)   GgaAffx.11659.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051056
Ensembl peptide - ENSGALP00000052043
Ensembl peptide - ENSGALP00000014599
NCBI entrez gene - 420538     See in Manteia.
RefSeq - NM_001080865
RefSeq Peptide - NP_001074334
swissprot - A0A1D5PGW7
swissprot - F1NUE0
Ensembl - ENSGALG00000008985
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sriENSDARG00000058593Danio rerio
 SRIENSG00000075142Homo sapiens
 SriENSMUSG00000003161Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PEF1 / penta-EF-hand domain containing 1 / Q8BFY6* / Q9UBV8* / Peflin *ENSGALG0000004051935
PDCD6 / programmed cell death 6 / O75340* / P12815* / Programmed cell death protein 6 *ENSGALG0000001340032
CAPNS2 / calpain small subunit 2 / Q96L46* / Q9D7J7*ENSGALG0000004505029
ENSGALG0000001113626


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IBA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0010459 negative regulation of heart rate IEA
 biological_processGO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus IEA
 biological_processGO:0042994 cytoplasmic sequestering of transcription factor IEA
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IEA
 biological_processGO:0051924 regulation of calcium ion transport IEA
 biological_processGO:0055118 negative regulation of cardiac muscle contraction IEA
 biological_processGO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity IEA
 biological_processGO:0086004 regulation of cardiac muscle cell contraction IEA
 biological_processGO:1901077 regulation of relaxation of muscle IEA
 biological_processGO:1901841 regulation of high voltage-gated calcium channel activity IEA
 biological_processGO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction IEA
 biological_processGO:2000678 negative regulation of transcription regulatory region DNA binding IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030018 Z disc IEA
 cellular_componentGO:0031982 vesicle IEA
 cellular_componentGO:0042584 chromaffin granule membrane IEA
 cellular_componentGO:0070062 extracellular exosome IEA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0004198 calcium-dependent cysteine-type endopeptidase activity IBA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA
 molecular_functionGO:0070491 repressing transcription factor binding IEA


Pathways (from Reactome)
Pathway description
Stimuli-sensing channels
Reduction of cytosolic Ca++ levels
Sodium/Calcium exchangers
Ion homeostasis
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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