ENSGALG00000009266


Gallus gallus

Features
Gene ID: ENSGALG00000009266
  
Biological name :FGA
  
Synonyms : FGA / fibrinogen alpha chain isoform 1 precursor
  
Possible biological names infered from orthology : E9PV24 / fibrinogen alpha chain / Fibrinogen alpha chain Fibrinopeptide A Fibrinogen alpha chain / P02671
  
Species: Gallus gallus
  
Chr. number: 4
Strand: -1
Band:
Gene start: 20484771
Gene end: 20491761
  
Corresponding Affymetrix probe sets: Gga.10203.1.S1_s_at (Chicken Array)   Gga.1023.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000015061
NCBI entrez gene - 396307     See in Manteia.
RefSeq - NM_001271911
RefSeq - NM_205356
RefSeq Peptide - NP_990687
RefSeq Peptide - NP_001258840
swissprot - F1P4V1
Ensembl - ENSGALG00000009266
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fgaENSDARG00000020741Danio rerio
 FGAENSG00000171560Homo sapiens
 FgaENSMUSG00000028001Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TNR / tenascin-R precursor / Q8BYI9* / Q92752* / tenascin R*ENSGALG0000000452617
FGB / fibrinogen beta chain / P02675* / Q8K0E8* / Fibrinogen beta chain Fibrinopeptide B Fibrinogen beta chain*ENSGALG0000000926217
FGG / fibrinogen gamma chain / P02679* / Q8VCM7*ENSGALG0000000926817
TNN / tenascin N / Q80Z71* / Q9UQP3*ENSGALG0000000453816
TNC / tenascin C / P24821* / Q80YX1*ENSGALG0000003999016
FGL1 / fibrinogen like 1 / Q08830*ENSGALG0000001360614
ANGPTL4 / angiopoietin like 4 / Q9BY76* / Q9Z1P8* / Angiopoietin-related protein 4 *ENSGALG0000000061914
ANGPTL3 / angiopoietin-related protein 3 precursor / Q9R182* / Q9Y5C1* / angiopoietin like 3* / Angiopoietin-related protein 3 ANGPTL3(17-224)*ENSGALG0000001097813
ANGPTL5 / Q86XS5* / angiopoietin like 5*ENSGALG0000001719113
TNXB* / P22105* / tenascin XB*ENSGALG0000004103113
ENSGALG0000001702912
FN1 / fibronectin 1 / P02751* / P11276* / Fibronectin Anastellin*ENSGALG0000000357811
ENSGALG0000004523810
ENSGALG0000004281910
ENSGALG0000003331410
ENSGALG0000002752010
ENSGALG0000004648210
ANGPT1L / angiopoietin-related protein 1-like precursor ENSGALG000000415029
ENSGALG000000418339


Protein motifs (from Interpro)
Interpro ID Name
 IPR002181  Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
 IPR012290  Fibrinogen, alpha/beta/gamma chain, coiled coil domain
 IPR014715  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 2
 IPR014716  Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
 IPR020837  Fibrinogen, conserved site
 IPR021996  Fibrinogen alpha C domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007160 cell-matrix adhesion IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0030168 platelet activation IEA
 biological_processGO:0031639 plasminogen activation IEA
 biological_processGO:0034116 positive regulation of heterotypic cell-cell adhesion IEA
 biological_processGO:0034622 cellular protein-containing complex assembly IEA
 biological_processGO:0042730 fibrinolysis IEA
 biological_processGO:0043152 induction of bacterial agglutination IEA
 biological_processGO:0045907 positive regulation of vasoconstriction IEA
 biological_processGO:0045921 positive regulation of exocytosis IEA
 biological_processGO:0050714 positive regulation of protein secretion IEA
 biological_processGO:0051258 protein polymerization IEA
 biological_processGO:0051592 response to calcium ion IEA
 biological_processGO:0065003 protein-containing complex assembly IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:0070527 platelet aggregation IEA
 biological_processGO:0072377 blood coagulation, common pathway IEA
 biological_processGO:0072378 blood coagulation, fibrin clot formation IEA
 biological_processGO:0090277 positive regulation of peptide hormone secretion IEA
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IEA
 cellular_componentGO:0005577 fibrinogen complex IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0031091 platelet alpha granule IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0030674 protein binding, bridging IEA
 molecular_functionGO:0050839 cell adhesion molecule binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Common Pathway of Fibrin Clot Formation
Integrin cell surface interactions
Integrin alphaIIb beta3 signaling
GRB2:SOS provides linkage to MAPK signaling for Integrins
p130Cas linkage to MAPK signaling for integrins
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
MAP2K and MAPK activation
Regulation of TLR by endogenous ligand
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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